FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term adult medulla-lobula neuron MeLo9 ID (Ontology) FBbt:20007233 (Fly Anatomy)
Definition Adult unilateral optic-lobe-intrinsic neuron with its soma posterior to the wedge (Schlegel et al., 2024; Dorkenwald et al., 2024). It bifurcates near the soma, sending one branch to the medulla and one to the lobula, without passing through the optic chiasm (Nern et al., 2025). It receives input, but also has presynapses, primarily in medulla layers M8-9 in around 30 columns (Nern et al., 2025). It also receives input in the lobula, in around 10 columns of layer 3 (Nern et al., 2025). Its predicted neurotransmitter is glutamate (Eckstein et al., 2024; Nern et al., 2025). There are approximately 40 of these cells per hemisphere (Nern et al., 2025).[ FlyBase:FBrf0259490 FlyBase:FBrf0260535 FlyBase:FBrf0260545 FlyBase:FBrf0260546 FlyBase:FBrf0262545 ]
Also Known As "adult CB3818 neuron" ; "CB3818" ; "LMa5" (for all, see Synonyms field below)
Comment Cell type from Schlegel et al. (2024), based on FlyWire v783 (FAFB) data (Dorkenwald et al., 2024; Schlegel et al., 2024), identified at light level by Nern et al. (2025). Soma location is based on the closest annotated neuropil region in FlyWire.
Links to External Ontologies
VFB:FBbt_20007233
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adult neuron
 |__adult glutamatergic neuron__________
adult interneuron                       |
 |__medulla-lobula connecting neuron____|
adult visual neuropil intrinsic neuron  |
 |__adult optic lobe intrinsic neuron___|
CNS neuron                              |
 |__supraesophageal ganglion neuron_____|
glutamatergic neuron                    |
 |__adult glutamatergic neuron__________|
                                        adult medulla-lobula neuron MeLo9
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Is a supraesophageal ganglion neuron
adult optic lobe intrinsic neuron
medulla-lobula connecting neuron
adult glutamatergic neuron
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VFB:FBbt_20007233