FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term descending neuron of the posterior brain DNp49 ID (Ontology) FBbt:20007549 (Fly Anatomy)
Definition Adult descending neuron with its soma in the brain, posterior-ventral to the mushroom body calyx (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the PSp3 lineage (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses in the ipsilateral and contralateral superior posterior slope, and the ipsilateral inferior clamp and inferior bridge, and presynapses in the gnathal ganglion (Schlegel et al., 2024; Dorkenwald et al., 2024). In the VNC, it follows the dorsal lateral tract of ventral cervical fasciculus (Sturner et al., 2024). Its predicted neurotransmitter is glutamate (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2024).[ FlyBase:FBrf0259490 FlyBase:FBrf0260535 FlyBase:FBrf0260546 ]
Also Known As "DNp49" ; "DNxn082"
Comment Type identified at light level and matched across EM datasets by Sturner et al. (2024). Pre- or post-synapse locations are the fewest regions that collectively contain at least 80 percent of all pre- or post-synapses of these neurons in FlyWire.
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VFB:FBbt_20007549
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adult neuron
 |__adult glutamatergic neuron________________
adult descending neuron                       |
 |__descending neuron of the posterior brain__|
CNS neuron                                    |
 |__supraesophageal ganglion neuron___________|
adult CNS neuron                              |
 |__descending neuron of the posterior brain__|
 |__adult PSp3 lineage neuron_________________|
glutamatergic neuron                          |
 |__adult glutamatergic neuron________________|
DPMl1 lineage neuron                          |
 |__adult PSp3 lineage neuron_________________|
                                              descending neuron of the posterior brain DNp49
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Is a supraesophageal ganglion neuron
descending neuron of the posterior brain
adult PSp3 lineage neuron
adult glutamatergic neuron
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VFB:FBbt_20007549