FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term descending neuron of the posterior brain DNp58 ID (Ontology) FBbt:20007550 (Fly Anatomy)
Definition Adult descending neuron with its soma in the brain, ventral to the mushroom body calyx (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the SMPpv2 lineage (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses and presynapses in the prow and the ipsilateral flange, and also has presynapses in the contralateral flange (Schlegel et al., 2024; Dorkenwald et al., 2024). In the VNC, it follows the curved ventrolateral tract (Sturner et al., 2024). Its predicted neurotransmitter is serotonin (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2024).[ FlyBase:FBrf0259490 FlyBase:FBrf0260535 FlyBase:FBrf0260546 ]
Also Known As "DNad003" ; "DNp58"
Comment Type identified at light level and matched across EM datasets by Sturner et al. (2024). Pre- or post-synapse locations are the fewest regions that collectively contain at least 80 percent of all pre- or post-synapses of these neurons in FlyWire.
Links to External Ontologies
VFB:FBbt_20007550
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serotonergic neuron
 |__adult serotonergic neuron_________________
adult descending neuron                       |
 |__descending neuron of the posterior brain__|
adult aminergic neuron                        |
 |__adult serotonergic neuron_________________|
CNS neuron                                    |
 |__supraesophageal ganglion neuron___________|
adult CNS neuron                              |
 |__descending neuron of the posterior brain__|
 |__adult SMPpv2 lineage neuron_______________|
CP1 lineage neuron                            |
 |__adult SMPpv2 lineage neuron_______________|
                                              descending neuron of the posterior brain DNp58
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Is a supraesophageal ganglion neuron
descending neuron of the posterior brain
adult serotonergic neuron
adult SMPpv2 lineage neuron
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VFB:FBbt_20007550