FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term descending neuron of the posterior brain DNp68 ID (Ontology) FBbt:20011358 (Fly Anatomy)
Definition Adult descending neuron with its soma in the posterior brain, ventral to the mushroom body calyx (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the SMPpv2 lineage (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses ipsilaterally in the superior medial protocerebrum and inferior clamp, and presynapses in the gnathal ganglion, the ipsilateral and contralateral superior posterior slope and the saddle (Schlegel et al., 2024; Dorkenwald et al., 2024). Within the VNC, it fasciculates with the median dorsal abdominal tract and sends output to multiple regions (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2024).[ FlyBase:FBrf0260535 FlyBase:FBrf0260546 ]
Also Known As "DNp68" ; "DNxn093"
Comment Type identified at light level and matched across EM datasets by Sturner et al. (2024). Pre- or post-synapse locations are those with the highest total count of these neurons in FlyWire FAFB.
Links to External Ontologies
VFB:FBbt_20011358
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cholinergic neuron
 |__adult cholinergic neuron__________________
adult neuron                                  |
 |__adult cholinergic neuron__________________|
adult descending neuron                       |
 |__descending neuron of the posterior brain__|
CNS neuron                                    |
 |__supraesophageal ganglion neuron___________|
adult CNS neuron                              |
 |__descending neuron of the posterior brain__|
 |__adult SMPpv2 lineage neuron_______________|
CP1 lineage neuron                            |
 |__adult SMPpv2 lineage neuron_______________|
                                              descending neuron of the posterior brain DNp68
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Is a supraesophageal ganglion neuron
descending neuron of the posterior brain
adult SMPpv2 lineage neuron
adult cholinergic neuron
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Synonyms
  • "DNp68" EXACT VFB_SYMBOL
    "DNxn093" EXACT
Secondary IDs
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VFB:FBbt_20011358