FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term adult lobula tangential neuron LT40 ID (Ontology) FBbt:20011446 (Fly Anatomy)
Definition Adult lobula tangential neuron of the LT40 group (Nern et al., 2025). It belongs to the VLPp&l1 posterior hemilineage (Nern et al., 2025). It receives input in the ipsilateral lateral accessory lobe, lobula layer 3, lobula layer 4, lobula layer 6, epaulette, vest, posterior ventrolateral protocerebrum, anterior ventrolateral protocerebrum, posterior lateral protocerebrum, inferior clamp, wedge, superior intermediate protocerebrum, superior posterior slope, inferior posterior slope, lobula layer 5A and lobula layer 5B, and the gnathal ganglion and saddle (Nern et al., 2025). It sends output to the ipsilateral lobula layer 3, lobula layer 4, epaulette, vest, posterior ventrolateral protocerebrum, anterior ventrolateral protocerebrum, posterior lateral protocerebrum, superior posterior slope, lobula layer 5A and lobula layer 5B, and the saddle (Nern et al., 2025). Its predicted neurotransmitter is GABA (Eckstein et al., 2024; Nern et al., 2025). There is one of these cells per hemisphere (Nern et al., 2025).[ FlyBase:FBrf0259490 FlyBase:FBrf0260535 FlyBase:FBrf0260546 FlyBase:FBrf0262545 ]
Also Known As "LT40"
Comment Cell type identified in multiple EM datasets (Schlegel et al., 2024; Dorkenwald et al., 2024; Nern et al., 2025). Synapse locations are given where each cell of this type in neuprint has at least 10 connections. Hemilineage information from neuprint, though original source not clear. Other information from Nern et al. (2025) supplements.
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VFB:FBbt_20011446
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GABAergic neuron
 |__adult GABAergic neuron__________________
projection neuron                           |
 |__wedge projection neuron_________________|
optic lobe tangential neuron                |
 |__lobula tangential neuron________________|
adult neuron                                |
 |__adult GABAergic neuron__________________|
adult visual projection neuron              |
 |__lobula tangential neuron________________|
DPLpv lineage neuron                        |
 |__adult VLPp&l1 lineage neuron____________|
adult interneuron                           |
 |__wedge projection neuron_________________|
 |__adult subesophageal zone output neuron__|
 |__adult visual centrifugal neuron_________|
input/output neuron                         |
 |__adult subesophageal zone output neuron__|
 |__adult visual centrifugal neuron_________|
adult CNS neuron                            |
 |__adult VLPp&l1 lineage neuron____________|
                                            adult lobula tangential neuron LT40
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Is a lobula tangential neuron
wedge projection neuron
adult subesophageal zone output neuron
adult VLPp&l1 lineage neuron
adult GABAergic neuron
adult visual centrifugal neuron
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VFB:FBbt_20011446