FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term hypomorphic allele - genetic evidence ID (Ontology) FBcv:0000289 (FlyBase CV)
Definition Allele inferred to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity from the observation that extra copies in the genome decrease the expressivity and/or penetrance of the phenotype. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype than the allele in trans to a deletion of the gene (1 copy)).[ FlyBase:FBrf0002371 FlyBase:FBrf0049147 ]
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Data Class Field Records
Alleles (FBal)  ALLELE_CLASS    2314
Alleles (FBal)  PROMOTED_CLASS    2138
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 Alleles
 hypomorphic allele - genetic evidence (all annotations which use CV term, excluding "NOT" statements)    2314
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  loss of function allele
   |__hypomorphic allele
       |__hypomorphic allele - genetic evidence  2368 rec.
           |__temperature conditional hypomorphic allele - genetic evidence 56 rec.
               |__cold sensitive hypomorphic allele - genetic evidence 6 rec.
               |__heat sensitive hypomorphic allele - genetic evidence 49 rec.
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