FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term gain of function allele ID (Ontology) FBcv:0000290 (FlyBase CV)
Definition An allele that either makes a normally functioning gene product but at higher levels or in a different spatial or temporal pattern to wild-type, or a product with increased or novel activity compared to wild-type.[ FlyBase:FBrf0049147 ]
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  ALLELE_CLASS     249
Alleles (FBal)  PROMOTED_CLASS     209
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 Full annotation statements 
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 Alleles
 gain of function allele (all annotations which use CV term, excluding "NOT" statements)     249
Spanning Tree (Parents/Children)
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  allele descriptor
   |__allele class
       |__gain of function allele  622 rec.
           |__antimorphic allele 261 rec.
           |   |__antimorphic allele - genetic evidence(+) 257 rec.
           |   |__antimorphic allele - molecular evidence(+) 2 rec.
           |   |__temperature conditional antimorphic allele(+) 5 rec.
           |__hypermorphic allele 84 rec.
           |   |__hypermorphic allele - genetic evidence(+) 59 rec.
           |   |__hypermorphic allele - molecular evidence(+) 25 rec.
           |   |__temperature conditional hypermorphic allele(+) 1 rec.
           |__neomorphic allele 62 rec.
           |   |__neomorphic allele - genetic evidence(+) 57 rec.
           |   |__neomorphic allele - molecular evidence(+) 5 rec.
           |   |__temperature conditional neomorphic allele(+) 4 rec.
           |__temperature conditional gain of function allele 24 rec.
               |__cold sensitive gain of function allele(+) 3 rec.
               |__heat sensitive gain of function allele(+) 20 rec.
               |__temperature conditional antimorphic allele(+) 5 rec.
               |__temperature conditional hypermorphic allele(+) 1 rec.
               |__temperature conditional neomorphic allele(+) 4 rec.
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