FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term antimorphic allele - genetic evidence ID (Ontology) FBcv:0000292 (FlyBase CV)
Definition An allele that is inferred to make a gene product that is antagonistic to the wild-type gene product from the observations that extra copies of the wild-type allele reduce the expressivity and/or penetrance of the phenotype. So, the phenotype over a deficiency is stronger than that over a wild-type allele, which in turn is stronger than that in the presence of a duplication of the wild-type locus. This test is similar to that used for hypomorphic alleles. An antimorph can be distinguished from a dominant hypermorph as only the former can be reverted to wild-type by deletion of the mutant allele.[ FlyBase:FBrf0002371 FlyBase:FBrf0049147 ]
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Data Class Field Records
Alleles (FBal)  ALLELE_CLASS     252
Alleles (FBal)  PROMOTED_CLASS     219
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 Alleles
 antimorphic allele - genetic evidence (all annotations which use CV term, excluding "NOT" statements)     252
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  gain of function allele
   |__antimorphic allele
       |__antimorphic allele - genetic evidence  257 rec.
           |__temperature conditional antimorphic allele - genetic evidence 5 rec.
               |__cold sensitive antimorphic allele - genetic evidence 3 rec.
               |__heat sensitive antimorphic allele - genetic evidence 2 rec.
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