FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term hypermorphic allele - genetic evidence ID (Ontology) FBcv:0000293 (FlyBase CV)
Definition An allele inferred to make either increased amounts of a normal gene product or a gene product with normal function but increased activity compared to wild-type from the observation that extra copies in the genome increase the expressivity and/or penetrance of the phenotype. Most commonly this evidence takes the form of experiments showing that homozygotes (2 copies) have a stronger phenotype than transheterozygotes to a deletion of the gene (1 copy).[ FlyBase:FBrf0002371 FlyBase:FBrf0049147 ]
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Data Class Field Records
Alleles (FBal)  ALLELE_CLASS      58
Alleles (FBal)  PROMOTED_CLASS      50
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 Alleles
 hypermorphic allele - genetic evidence (all annotations which use CV term, excluding "NOT" statements)      58
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  gain of function allele
   |__hypermorphic allele
       |__hypermorphic allele - genetic evidence  59 rec.
           |__temperature conditional hypermorphic allele - genetic evidence 1 rec.
               |__cold sensitive hypermorphic allele - genetic evidence
               |__heat sensitive hypermorphic allele - genetic evidence
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