FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term abnormal DNA repair ID (Ontology) FBcv:0000423 (FlyBase CV)
Definition Phenotype that is any abnormality in DNA repair (GO:0006281). 'DNA repair' is defined as: 'The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.'[ PubMed:11563486 ]
Also Known As "DNA repair defective"
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Data Class Field Records
Alleles (FBal)  PHENOTYPIC_CLASS     132
Constructs (FBtp)  PHENOTYPIC_CLASS      25
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Relevant FlyBase reports
 Alleles Constructs
 abnormal DNA repair (all annotations which use CV term, excluding "NOT" statements)     132     25
     abnormal DNA repair | adult stage      16      9
     abnormal DNA repair | adult stage | conditional       7      5
     abnormal DNA repair | adult stage | dominant       2       --
     abnormal DNA repair | adult stage | recessive       1       --
     abnormal DNA repair | adult stage | somatic clone       1       --
     abnormal DNA repair | conditional       1       --
     abnormal DNA repair | dominant       2       --
     abnormal DNA repair | dominant | parental effect       3      3
     abnormal DNA repair | embryonic stage       1       --
     abnormal DNA repair | female       1       --
     abnormal DNA repair | first instar larval stage       1       --
     abnormal DNA repair | larval stage      15      4
     abnormal DNA repair | oogenesis      11       --
     abnormal DNA repair | pupal stage       2       --
     abnormal DNA repair | recessive       1       --
     abnormal DNA repair | third instar larval stage       7      5
     abnormal DNA repair | third instar larval stage | conditional       3      2
Spanning Tree (Parents/Children)
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  phenotype
   |__abnormal stress response
       |__abnormal DNA repair  157 rec.
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