FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term cisplatin ID (Ontology) FBcv:0000576 (FlyBase CV)
Definition A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups) (from CHEBI).
Also Known As "mutation induced by cisplatin exposure"
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Data Class Field Records
Aberrations (FBab)  MUTAGEN       6
Alleles (FBal)  MUTAGEN      29
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 Aberrations Alleles
 cisplatin (all annotations which use CV term, excluding "NOT" statements)       6     29
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  origin of mutation
   |__chemical
       |__cisplatin  35 rec.
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Synonyms
  • "cis-dichlorodiammineplatinum(II)" RELATED
    "mutation induced by cisplatin exposure" EXACT
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