FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term heat sensitive loss of function allele ID (Ontology) FBcv:0000746 (FlyBase CV)
Definition An allele that at high temperatures but not low temperatures, either makes no functional gene product, makes reduced levels of a normally functioning gene product or makes a gene product with reduced activity compared to wild-type.[ FlyBase:FBrf0049147 ]
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Data Class Field Records
Alleles (FBal)  ALLELE_CLASS      46
Alleles (FBal)  PROMOTED_CLASS      44
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 Alleles
 heat sensitive loss of function allele (all annotations which use CV term, excluding "NOT" statements)      46
Spanning Tree (Parents/Children)
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  loss of function allele
   |__temperature conditional loss of function allele
       |__heat sensitive loss of function allele  100 rec.
           |__heat sensitive amorphic allele 5 rec.
           |   |__heat sensitive amorphic allele - genetic evidence 3 rec.
           |   |__heat sensitive amorphic allele - molecular evidence 2 rec.
           |__heat sensitive hypomorphic allele 50 rec.
               |__heat sensitive hypomorphic allele - genetic evidence 49 rec.
               |__heat sensitive hypomorphic allele - molecular evidence 1 rec.
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Is a temperature conditional loss of function allele
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