FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term temperature conditional gain of function allele ID (Ontology) FBcv:0000748 (FlyBase CV)
Definition An allele that at some temperatures but not others, either makes a normally functioning gene product but at higher levels or in a different spatial or temporal pattern to wild-type, or a product with increased or novel activity compared to wild-type.[ FlyBase:FBrf0049147 ]
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Spanning Tree (Parents/Children)
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  allele class
   |__gain of function allele
       |__temperature conditional gain of function allele  24 rec.
           |__cold sensitive gain of function allele 3 rec.
           |   |__cold sensitive antimorphic allele(+) 3 rec.
           |   |__cold sensitive hypermorphic allele(+)
           |   |__cold sensitive neomorphic allele(+)
           |__heat sensitive gain of function allele 20 rec.
           |   |__heat sensitive antimorphic allele(+) 2 rec.
           |   |__heat sensitive hypermorphic allele(+)
           |   |__heat sensitive neomorphic allele(+) 4 rec.
           |__temperature conditional antimorphic allele 5 rec.
           |   |__cold sensitive antimorphic allele(+) 3 rec.
           |   |__heat sensitive antimorphic allele(+) 2 rec.
           |   |__temperature conditional antimorphic allele - genetic evidence(+) 5 rec.
           |   |__temperature conditional antimorphic allele - molecular evidence(+)
           |__temperature conditional hypermorphic allele 1 rec.
           |   |__cold sensitive hypermorphic allele(+)
           |   |__heat sensitive hypermorphic allele(+)
           |   |__temperature conditional hypermorphic allele - genetic evidence(+) 1 rec.
           |   |__temperature conditional hypermorphic allele - molecular evidence(+) 1 rec.
           |__temperature conditional neomorphic allele 4 rec.
               |__cold sensitive neomorphic allele(+)
               |__heat sensitive neomorphic allele(+) 4 rec.
               |__temperature conditional neomorphic allele - genetic evidence(+) 4 rec.
               |__temperature conditional neomorphic allele - molecular evidence(+)
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