FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term temperature conditional hypomorphic allele - genetic evidence ID (Ontology) FBcv:0000754 (FlyBase CV)
Definition An allele inferred from genetic evidence to have normal activity at some temperatures (permissive temperatures) but at other temperatures to make a gene product with normal function but in a lesser amount or with lowered activity (non-permissive temperatures). The genetic evidence must consist of an observation extra copies in the genome decrease the expressivity and/or penetrance of the phenotype at non-permissive temperatures. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype at non-permissive temperatures than the allele in trans to a deletion of the gene (1 copy)).[ FlyBase:FBrf0002371 FlyBase:FBrf0049147 ]
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Data Class Field Records
Alleles (FBal)  ALLELE_CLASS       1
Alleles (FBal)  PROMOTED_CLASS       1
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 temperature conditional hypomorphic allele - genetic evidence (all annotations which use CV term, excluding "NOT" statements)       1
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hypomorphic allele
 |__hypomorphic allele - genetic evidence________
 |__temperature conditional hypomorphic allele___|
temperature conditional loss of function allele  |
 |__temperature conditional hypomorphic allele___|
                                                 temperature conditional hypomorphic allele - genetic evidence  56 rec.
                                                  |__cold sensitive hypomorphic allele - genetic evidence 6 rec.
                                                  |__heat sensitive hypomorphic allele - genetic evidence 49 rec.
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Is a hypomorphic allele - genetic evidence
temperature conditional hypomorphic allele
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