FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term 1,4-dimethanesulfonoxybutane ID (Ontology) FBcv:0000814 (FlyBase CV)
Definition A methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant (from CHEBI).
Also Known As "mutation induced by 1,4-dimethanesulfonoxybutane exposure" ; "mutation induced by busulfan exposure"
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Data Class Field Records
Alleles (FBal)  MUTAGEN       1
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 1,4-dimethanesulfonoxybutane (all annotations which use CV term, excluding "NOT" statements)       1
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  chemical
   |__alkylating agent
       |__1,4-dimethanesulfonoxybutane  1 rec.
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Is a alkylating agent
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Synonyms
  • "busulfan" RELATED
    "CB2041" RELATED
    "mutation induced by 1,4-dimethanesulfonoxybutane exposure" EXACT
    "mutation induced by busulfan exposure" EXACT
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