FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term p-N,N-di-(2-chloroethyl)aminophenylbutyric acid ID (Ontology) FBcv:0000815 (FlyBase CV)
Definition A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia (from CHEBI).
Also Known As "chlorambucil" ; "mutation induced by chlorambucil exposure" ; "mutation induced by p-N,N-di-(2-chloroethyl)aminophenylbutyric acid exposure"
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Data Class Field Records
Alleles (FBal)  MUTAGEN       1
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 p-N,N-di-(2-chloroethyl)aminophenylbutyric acid (all annotations which use CV term, excluding "NOT" statements)       1
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  alkylating agent
   |__nitrogen mustard
       |__p-N,N-di-(2-chloroethyl)aminophenylbutyric acid  1 rec.
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Is a nitrogen mustard
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Synonyms
  • "CB1348" RELATED
    "chlorambucil" EXACT
    "mutation induced by chlorambucil exposure" EXACT
    "mutation induced by p-N,N-di-(2-chloroethyl)aminophenylbutyric acid exposure" EXACT
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