FB2025_05 , released December 11, 2025

CV Term Report

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General Information
Term	site specific cleavage	ID (Ontology)	FBcv:0003007 (FlyBase CV)
Definition	Sequence change induced by a cleavage event that is caused by an endonuclease that recognizes and cleaves specific sequences in double stranded DNA causing double-strand breaks (DSB).[ FlyBase:FBrf0202435 ]
Also Known As	"change induced by site specific cleavage"
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Spanning Tree (Parents/Children)

  allele descriptor
   |__origin of mutation
       |__site specific cleavage  17981 rec.
           |__CRISPR/Cas9 17252 rec.
           |__I-CreI 207 rec.
           |__I-SceI 524 rec.
           |__TALEN 107 rec.
           |__ZFN 3 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	origin of mutation
Part of
Synonyms & Secondary IDs
Synonyms
	"change induced by site specific cleavage" EXACT
Secondary IDs

External Crossreferences & Linkouts