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General Information
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| Term |
chromophore-assisted light inactivation tag |
ID (Ontology) |
FBcv:0005041 (FlyBase CV) |
| Definition |
Sequence that forms part of the protein encoded by a transgenic locus or modified endogenous locus and which allows a protein to be inactivated by the chromophore-assisted light inactivation (CALI) technique. The tag consists of a peptide sequence that specifically binds a membrane-permeable, chromophore-containing molecule. When activated using a pulse of high-intensity light that is absorbed by the chromophore but not by cellular components, the membrane-permeable molecule generates short-lived reactive oxygen species which inactivate the tagged protein to which the molecule is bound via the chromophore-assisted light inactivation tag.[ PubMed:14625562 PubMed:16605242 PubMed:21226520 PubMed:3399501 ] |
| Also Known As |
"CALI tag" |
| Comment |
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Links to External Ontologies
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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No relevant records available
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Full annotation statements | Relevant FlyBase reports |
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| Genes | Experimental Tools |
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chromophore-assisted light inactivation tag (all annotations which use CV term, excluding "NOT" statements) | 1 | 5 | encodes tool | chromophore-assisted light inactivation tag | -- | 3 | tagged with | chromophore-assisted light inactivation tag | -- | 4 |
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Relationships