General Information
Term	binary expression system component	ID (Ontology)	FBcv:0005058 (FlyBase CV)
Definition	Component that forms part of a binary expression system. This system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. In addition, a specific repressor protein may be available which prevents the transactivator from driving expression, allowing further refinement of the expression pattern of the responder.[ FlyBase:FBrf0216478 ]
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General Information

Term

binary expression system component

ID (Ontology)

FBcv:0005058 (FlyBase CV)

Definition

Component that forms part of a binary expression system. This system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. In addition, a specific repressor protein may be available which prevents the transactivator from driving expression, allowing further refinement of the expression pattern of the responder.[ FlyBase:FBrf0216478 ]

Comment

Links to External Ontologies

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

  descriptor
   |__experimental tool descriptor
       |__binary expression system component  75 rec.
           |__binary expression system - driver 53 rec.
           |   |__binary expression system - conditional driver(+) 16 rec.
           |__binary expression system - regulatory region 15 rec.
           |__binary expression system - repressor 7 rec.
               |__binary expression system - conditional repressor(+) 2 rec.

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