FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term genome engineering tool ID (Ontology) FBcv:0005075 (FlyBase CV)
Definition Sequence that forms all or part of a transgenic locus or modified endogenous locus and which can be used to an modify an organism's genetic material in a defined manner. Genome engineering can occur on many levels, ranging from targeting of an individual gene with a small modification through to the engineering of chromosomal rearrangements. In addition to the manipulation of endogenous loci, genome engineering can also be used to introduce exogenous material into the genome, and to manipulate such exogenous material already introduced the genome.[ FlyBase:FBrf0231034 ]
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 Experimental Tools
 genome engineering tool (all annotations which use CV term, excluding "NOT" statements)      13
     encodes tool | genome engineering tool      12
     tagged with | genome engineering tool       1
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  descriptor
   |__experimental tool descriptor
       |__genome engineering tool  519 rec.
           |__docking element 15 rec.
           |__integrase 53 rec.
           |__integrase target site 10 rec.
           |__nuclease 30 rec.
           |   |__meganuclease 4 rec.
           |   |__RNA-guided nuclease(+) 12 rec.
           |__nuclease target site 2 rec.
           |__recombinase 254 rec.
           |   |__conditional recombinase(+) 5 rec.
           |__recombinase target site 29 rec.
           |__RMCE donor element 81 rec.
           |__RMCE target element 37 rec.
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