FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term small molecule-regulated RNA-guided nuclease ID (Ontology) FBcv:0009039 (FlyBase CV)
Definition An enzyme that catalyzes hydrolysis of DNA in a site-specific manner, where the specificity is determined by a guide RNA that contains sequence complementary to the DNA sequence of interest (rather than being an inherent property of the nuclease itself) and where the nuclease activity can be regulated by binding to a small molecule, such as an ion or ligand.
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 small molecule-regulated RNA-guided nuclease (all annotations which use CV term, excluding "NOT" statements)       1
     encodes tool | small molecule-regulated RNA-guided nuclease       1
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  RNA-guided nuclease
   |__conditional RNA-guided nuclease
       |__small molecule-regulated RNA-guided nuclease  1 rec.
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Is a conditional RNA-guided nuclease
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