FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term human immunodeficiency virus infectious disease ID (Ontology) DOID:526 (Human Disease)
Definition A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.
Also Known As "HIV infection"
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Data Class Field Records
Alleles (FBal)  HUMAN_DISEASE_INTERACTIONS      16
Human Disease Models (FBhh)  DOID       1
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Relevant FlyBase reports
 Alleles Genes Human Disease Models
 human immunodeficiency virus infectious disease      16     11      1
 ameliorates | human immunodeficiency virus infectious disease      10       --       --
 exacerbates | human immunodeficiency virus infectious disease       3       --       --
 model of | human immunodeficiency virus infectious disease       3       --       --
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  disease by infectious agent
   |__viral infectious disease
       |__human immunodeficiency virus infectious disease  28 rec.
           |__acquired immunodeficiency syndrome
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Synonyms
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Secondary IDs
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ICD10CM:B20
ICD9CM:042
ICD9CM:042-042.99
MESH:D015658
NCI:C3108
SNOMEDCT_US_2023_03_01:86406008
UMLS_CUI:C0019693