FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term tauopathy ID (Ontology) DOID:680 (Human Disease)
Definition A neurodegenerative disease that has_material_basis_in the pathological aggregation of tau protein in so-called neurofibrillary tangles (NFT) in the human brain.
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DO.org
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Data Class Field Records
Alleles (FBal)  HUMAN_DISEASE_INTERACTIONS     745
Human Disease Models (FBhh)  DOID      12
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Human Disease Models
 tauopathy     754    426     12
 ameliorates | tauopathy     251       --       --
 exacerbates | tauopathy     381       --       --
 model of | tauopathy     134       --       --
 DOES NOT ameliorate | tauopathy       1       --       --
 DOES NOT model | tauopathy       3       --       --
Spanning Tree (Parents/Children)
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  central nervous system disease
   |__neurodegenerative disease
       |__tauopathy  2016 rec.
           |__Alzheimer's disease 957 rec.
           |   |__Alzheimer's disease 1 588 rec.
           |   |__Alzheimer's disease 2 9 rec.
           |   |__Alzheimer's disease 3 8 rec.
           |   |__Alzheimer's disease 4 3 rec.
           |   |__Alzheimer's disease 5
           |   |__Alzheimer's disease 6
           |   |__Alzheimer's disease 7
           |   |__Alzheimer's disease 8
           |   |__Alzheimer's disease 9 1 rec.
           |   |__Alzheimer's disease 10
           |   |__Alzheimer's disease 11
           |   |__Alzheimer's disease 12
           |   |__Alzheimer's disease 13
           |   |__Alzheimer's disease 14
           |   |__Alzheimer's disease 15
           |   |__Alzheimer's disease 16
           |   |__Alzheimer's disease 17
           |   |__Alzheimer's disease 18 3 rec.
           |   |__Alzheimer's disease 19
           |__chronic traumatic encephalopathy
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MESH:D024801
UMLS_CUI:C0949664