FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term frontotemporal dementia ID (Ontology) DOID:9255 (Human Disease)
Definition A dementia characterized by progressive neuronal loss predominantly involving the frontal and/or temporal lobes of the brain resulting in a gradual and progressive decline in behavior or language.
Also Known As "frontotemporal lobar degeneration" ; "multiple system tauopathy with presenile dementia" ; "pallidopontonigral degeneration" (for all, see Synonyms field below)
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DO.org
Annotations
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Data Class Field Records
Alleles (FBal)  HUMAN_DISEASE_INTERACTIONS      77
Human Disease Models (FBhh)  DOID       2
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Relevant FlyBase reports
 Alleles Genes Human Disease Models
 frontotemporal dementia      93     44      2
 ameliorates | frontotemporal dementia      16       --       --
 exacerbates | frontotemporal dementia      34       --       --
 for disease ribbon | frontotemporal dementia       --       2       --
 model of | frontotemporal dementia      33      2       --
 DOES NOT ameliorate | frontotemporal dementia       3       --       --
 DOES NOT model | frontotemporal dementia      10       --       --
Spanning Tree (Parents/Children)
Only view relationship: 
cognitive disorder
 |__dementia____________________
central nervous system disease  |
 |__brain disease_______________|
                                frontotemporal dementia  180 rec.
                                 |__corticobasal degeneration syndrome
                                 |__frontotemporal dementia and/or amyotrophic lateral sclerosis 7 41 rec.
                                 |__GRN-related frontotemporal lobar degeneration with Tdp43 inclusions
                                 |__Pick's disease 6 rec.
                                 |__primary progressive aphasia
                                     |__logopenic progressive aphasia
                                     |__progressive non-fluent aphasia
                                     |__semantic dementia
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Is a dementia
brain disease
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Synonyms
  • "frontotemporal lobar degeneration" EXACT
    "multiple system tauopathy with presenile dementia" EXACT
    "pallidopontonigral degeneration" EXACT
    "Wilhemsen-Lynch disease" EXACT
Secondary IDs
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GARD:8436
MESH:C563003
MIM:600274
ORDO:282
SNOMEDCT_US_2023_03_01:42369001
UMLS_CUI:C0520716