FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term optic lobe pioneer neuron ID (Ontology) FBbt:00003703 (Fly Anatomy)
Definition Neuron located in the distal region of the optic lobe (Tix et al., 1989), which persists through development and pioneers Bolwig's nerve. In the developing optic lobe, at larval stage, this group of three neurons are fully differentiated before there is any detectable fiber growth in the rest of the optic lobe. Following this, other neuron projections from the optic lobe follow the same path as these pioneers and fasciculate to form Bolwig's nerve (Tix et al., 1989). They have their cell bodies located together on the ventrolateral side of the larval optic neuropil (Larderet et al., 2017).[ FlyBase:FBrf0049574 FlyBase:FBrf0237760 ]
Also Known As "OLP"
Comment Tix et al. (1989) state that in 57 out of 62 third instar larval brain samples only three optic pioneer neurons were observed. However, they found three brains showing four of these neurons, and two cases displaying only two. Larderet et al., 2017 also found variability - three in the left hemisphere, four in the right hemisphere.
Links to External Ontologies
VFB:FBbt_00003703
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Data Class Field Records
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       1
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 optic lobe pioneer neuron (all annotations which use CV term, excluding "NOT" statements)       1      1
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neuron
 |__pioneer neuron___________________
efferent neuron                      |
 |__larval efferent neuron___________|
CNS neuron                           |
 |__supraesophageal ganglion neuron__|
larval CNS neuron                    |
 |__larval efferent neuron___________|
                                     optic lobe pioneer neuron  13 rec.
                                      |__optic lobe pioneer neuron 1 3 rec.
                                      |__optic lobe pioneer neuron 2 10 rec.
                                      |__optic lobe pioneer neuron 3 5 rec.
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Is a supraesophageal ganglion neuron
pioneer neuron
larval efferent neuron
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VFB:FBbt_00003703