FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term proventriculus ID (Ontology) FBbt:00005752 (Fly Anatomy)
Definition Bulb-shaped organ at the junction of the foregut and midgut that regulates the passage of food into the midgut. The proventriculus folds back on itself to produce three epithelial layers: internally the posterior region of the esophagus, an intermediate (recurrent) layer, derived from the ectodermal foregut and the midgut, and an external anterior projection of the endodermal midgut, which grows over the esophageal region. The inner two layers form the gastric valve (cardial valve) while the outer layer is defined as the wall of the proventriculus. The cuticle that lines the inner wall is thicker than other regions in the cardia, and it forms several longitudinal folds, causing the esophageal lumen to appear irregular in cross section. Between the intermediate and outer wall is the cardia lumen, which opens posteriorly into the lumen of the midgut. The anterior region secretes the peritrophic membrane into the cardia lumen. The epithelium is surrounded by a thin tunic of striated muscle fibers.[ FlyBase:FBrf0007732 FlyBase:FBrf0007735 FlyBase:FBrf0048518 FlyBase:FBrf0064792 ]
Also Known As "cardia"
Comment This structure is more correctly referred to as the 'cardia'. Strictly, proventriculus refers to a modification of the foregut, just anterior to the stomodeal valve, found in many insects. Drosophila has no such foregut modification (Miller, 1950). However, the term 'proventriculus' is the one most commonly used for this structure.
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Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN       3
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       8
Insertions (FBti)  PHENOTYPE_MANIFEST_IN       1
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 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Images Insertions Constructs
 proventriculus (all annotations which use CV term, excluding "NOT" statements)       3     13      1      9     10
     proventriculus | adult stage       1       --       --       --       --
Spanning Tree (Parents/Children)
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organ system subdivision
 |__gut section_____________
multicellular structure     |
 |__multi-tissue structure__|
                            proventriculus  836 rec.
                             |__adult proventriculus 86 rec.
                             |__embryonic proventriculus 448 rec.
                             |__embryonic/larval proventriculus 293 rec.
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Is a multi-tissue structure
gut section
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