FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term larval multidendritic class IV neuron ID (Ontology) FBbt:00007275 (Fly Anatomy)
Definition Larval dendritic arborizing neuron with a highly complex branching pattern that completely fills large regions of the body wall with its arbors (Grueber et al., 2002). Each cell may have 800-900 terminal branches and more than 6 branch orders (Grueber et al., 2002). The three subtypes innervate different regions of the body wall (Grueber et al., 2002) and the nociceptive neuropil of the ventral nerve cord (Li et al., 2019). They are nociceptive neurons and some can respond to noxious mechanical and/or heat stimuli (Hwang et al., 2007; Robertson et al., 2013).[ FlyBase:FBrf0148966 FlyBase:FBrf0200914 FlyBase:FBrf0223267 FlyBase:FBrf0244259 ]
Also Known As "class IV da" ; "class IV dendritic arborising neuron" ; "class IV dendritic arborizing neuron" (for all, see Synonyms field below)
Comment
Links to External Ontologies
VFB:FBbt_00007275
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN     404
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION      28
Insertions (FBti)  PHENOTYPE_MANIFEST_IN      69
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN     238
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Insertions Constructs
 larval multidendritic class IV neuron (all annotations which use CV term, excluding "NOT" statements)     410     16     96    256
     larval multidendritic class IV neuron | cell autonomous | larval stage       3       --       1      2
     larval multidendritic class IV neuron | cell autonomous | somatic clone       3       --       1       --
     larval multidendritic class IV neuron | cell non-autonomous | somatic clone | third instar larval stage       5       --       --       7
     larval multidendritic class IV neuron | cell non-autonomous | third instar larval stage      12       --       --       9
     larval multidendritic class IV neuron | conditional       2       --       --       2
     larval multidendritic class IV neuron | embryonic stage       6       --       2       --
     larval multidendritic class IV neuron | first instar larval stage       3       --       1       --
     larval multidendritic class IV neuron | larval stage      38       --       2     31
     larval multidendritic class IV neuron | larval stage | conditional       2       --       --       1
     larval multidendritic class IV neuron | larval stage | heat sensitive       2       --       --       1
     larval multidendritic class IV neuron | larval stage | progressive       3       --       2       --
     larval multidendritic class IV neuron | larval stage | somatic clone       5       --       --       --
     larval multidendritic class IV neuron | late third instar larval stage       2       --       --       --
     larval multidendritic class IV neuron | P-stage      30       --       1     24
     larval multidendritic class IV neuron | P-stage | somatic clone       8       --       --       --
     larval multidendritic class IV neuron | prepupal stage       1       --       1       --
     larval multidendritic class IV neuron | pupal stage      15       --       --      14
     larval multidendritic class IV neuron | pupal stage | somatic clone       3       --       --       --
     larval multidendritic class IV neuron | RU486 conditional       3       --       --       3
     larval multidendritic class IV neuron | second instar larval stage       2       --       --       2
     larval multidendritic class IV neuron | somatic clone      31       --       9      9
     larval multidendritic class IV neuron | somatic clone | third instar larval stage      16       --       --       2
     larval multidendritic class IV neuron | somatic clone | third instar larval stage | heat sensitive       2       --       --       1
     larval multidendritic class IV neuron | third instar larval stage     130       --      44     64
     larval multidendritic class IV neuron | third instar larval stage | conditional       5       --       2      2
     larval multidendritic class IV neuron | third instar larval stage | heat sensitive       2       --       --       2
     larval multidendritic class IV neuron | wandering third instar larval stage       5       --       --       5
Spanning Tree (Parents/Children)
Only view relationship:
sensory neuron
 |__nociceptive neuron____________
multidendritic neuron             |
 |__dendritic arborizing neuron___|
 |__larval multidendritic neuron__|
primary neuron                    |
 |__larval multidendritic neuron__|
nociceptive system neuron         |
 |__nociceptive neuron____________|
embryonic/larval sensory neuron   |
 |__larval multidendritic neuron__|
larval PNS neuron                 |
 |__larval multidendritic neuron__|
                                  larval multidendritic class IV neuron  1519 rec.
                                   |__abdominal anterior ventral multidendritic neuron vdaa 181 rec.
                                   |   |__abdominal 1 anterior ventral multidendritic neuron vdaa
                                   |   |__abdominal 2 anterior ventral multidendritic neuron vdaa
                                   |   |__abdominal 3 anterior ventral multidendritic neuron vdaa
                                   |   |__abdominal 4 anterior ventral multidendritic neuron vdaa
                                   |   |__abdominal 5 anterior ventral multidendritic neuron vdaa
                                   |   |__abdominal 6 anterior ventral multidendritic neuron vdaa
                                   |   |__abdominal 7 anterior ventral multidendritic neuron vdaa
                                   |__larval dorsal multidendritic neuron ddaC 797 rec.
                                   |   |__abdominal dorsal multidendritic neuron ddaC(+) 147 rec.
                                   |   |__mesothoracic dorsal multidendritic neuron ddaC
                                   |   |__metathoracic dorsal multidendritic neuron ddaC
                                   |   |__prothoracic dorsal multidendritic neuron ddaC
                                   |__larval ventral multidendritic neuron vdaB 118 rec.
                                       |__abdominal ventral multidendritic neuron vdaB(+) 12 rec.
                                       |__mesothoracic ventral multidendritic neuron vdaB
                                       |__metathoracic ventral multidendritic neuron vdaB
                                       |__prothoracic ventral multidendritic neuron vdaB
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Is a dendritic arborizing neuron
larval multidendritic neuron
nociceptive neuron
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Synonyms
Secondary IDs
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VFB:FBbt_00007275