FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term larval octopaminergic VPM neuron ID (Ontology) FBbt:00047556 (Fly Anatomy)
Definition Octopaminergic, bilaterally-paired neuron of the larval central nervous system. Their cell bodies are found in the ventral cortex of the three subesophageal neuromeres (Selcho et al., 2014), the three thoracic neuromeres and the first abdominal neuromere, somewhat ventro-lateral to the VM fascicles (Vomel and Wegener, 2008). They form a cluster with the VUM neuron cell bodies of the same neuromere, but unlike the VUM neurons, the VPM neurons are restricted to the CNS. Most VPM neurons project anteriorly and cross the midline to arborize mainly in the contralateral neuropil (Selcho et al., 2012; Selcho et al., 2014).[ FlyBase:FBrf0210246 FlyBase:FBrf0219406 FlyBase:FBrf0225919 ]
Also Known As "paramedial TDC2 neuron" ; "pmTDC2" ; "ventral paired medial neuron" (for all, see Synonyms field below)
Comment For neurotransmitter expression analysis, Vomel and Wegener (2008) used Tdc2-GAL4 (tyrosine decarboxylase - implies presence of tyramine) and anti-Tbh (tyramine beta-hydroxylase - implies presence of octopamine). Selcho et al. (2012) used Tdc2-GAL4, validated with anti-Tbh, anti-p-tyramine and anti-conjugated octopamine, to visualize tyraminergic and octopaminergic neurons.
Links to External Ontologies
VFB:FBbt_00047556
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larval neuron
 |__larval CNS neuron_____________
octopaminergic neuron             |
 |__larval octopaminergic neuron__|
larval aminergic neuron           |
 |__larval octopaminergic neuron__|
 |__larval tyraminergic neuron____|
CNS neuron                        |
 |__larval CNS neuron_____________|
tyraminergic neuron               |
 |__larval tyraminergic neuron____|
                                  larval octopaminergic VPM neuron  7 rec.
                                   |__larval labial VPM neuron
                                   |__larval mandibular VPM neuron
                                   |   |__larval mandibular VPM neuron 1
                                   |   |__larval mandibular VPM neuron 2
                                   |__larval maxillary VPM neuron 7 rec.
                                   |__larval mesothoracic VPM neuron
                                   |__larval metathoracic VPM neuron
                                   |__larval prothoracic VPM neuron
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Is a larval octopaminergic neuron
larval tyraminergic neuron
larval CNS neuron
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VFB:FBbt_00047556