FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term larval down and back neuron ID (Ontology) FBbt:00047725 (Fly Anatomy)
Definition Cholinergic somatosensory interneuron that arborizes in the nociceptive neuropil and receives input from class IV dendritic arborizing neurons (Gerhard et al., 2017; Burgos et al., 2018). From a laterally-located cell body, it projects ventromedially to the nociceptive neuropil and arborizes profusely; then a single process projects back laterally and dorsally towards the cell body (Burgos et al., 2018). It is involved in activating bending and rolling behavior in response to nociceptive stimuli, such as noxious heat (Burgos et al., 2018) and it is a premotor neuron (Zarin et al., 2019).[ FlyBase:FBrf0237057 FlyBase:FBrf0238464 FlyBase:FBrf0244727 ]
Also Known As "A09l" ; "DnB neuron" ; "down-and-back-1"
Comment DnBs seem to have peptidergic output sites, but peptide identity unknown (Burgos et al., 2018).
Links to External Ontologies
VFB:FBbt_00047725
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       2
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Insertions Constructs
 larval down and back neuron (all annotations which use CV term, excluding "NOT" statements)       2      1
Spanning Tree (Parents/Children)
Only view relationship: 
larval neuron
 |__larval premotor neuron_____________
 |__larval cholinergic neuron__________|
interneuron                            |
 |__larval interneuron_________________|
cholinergic neuron                     |
 |__larval cholinergic neuron__________|
sensory system neuron                  |
 |__nociceptive system neuron__________|
NB3-5 lineage primary neuron           |
 |__lineage NB3-5 primary interneuron__|
premotor neuron                        |
 |__larval premotor neuron_____________|
primary interneuron                    |
 |__lineage NB3-5 primary interneuron__|
larval CNS neuron                      |
 |__larval interneuron_________________|
                                       larval down and back neuron  3 rec.
                                        |__larval abdominal 1 down and back neuron
                                        |__larval abdominal 2 down and back neuron
                                        |__larval abdominal 3 down and back neuron
                                        |__larval abdominal 4 down and back neuron
                                        |__larval abdominal 5 down and back neuron
                                        |__larval abdominal 6 down and back neuron
                                        |__larval metathoracic down and back neuron
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a lineage NB3-5 primary interneuron
nociceptive system neuron
larval premotor neuron
larval interneuron
larval cholinergic neuron
Part of larval ventral nerve cord
hide Synonyms & Secondary IDs
Synonyms
Secondary IDs
hide External Crossreferences & Linkouts
VFB:FBbt_00047725