FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term temperature conditional loss of function allele ID (Ontology) FBcv:0000745 (FlyBase CV)
Definition An allele that at some temperatures but not others either makes no functional gene product or makes reduced levels of a normally functioning gene product or makes a gene product with reduced activity compared to wild-type.[ FlyBase:FBrf0049147 ]
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  ALLELE_CLASS       6
Alleles (FBal)  PROMOTED_CLASS       6
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 Alleles
 temperature conditional loss of function allele (all annotations which use CV term, excluding "NOT" statements)       6
Spanning Tree (Parents/Children)
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  allele class
   |__loss of function allele
       |__temperature conditional loss of function allele  122 rec.
           |__cold sensitive loss of function allele 11 rec.
           |   |__cold sensitive amorphic allele(+) 1 rec.
           |   |__cold sensitive hypomorphic allele(+) 7 rec.
           |__heat sensitive loss of function allele 100 rec.
           |   |__heat sensitive amorphic allele(+) 5 rec.
           |   |__heat sensitive hypomorphic allele(+) 50 rec.
           |__temperature conditional amorphic allele 8 rec.
           |   |__cold sensitive amorphic allele(+) 1 rec.
           |   |__heat sensitive amorphic allele(+) 5 rec.
           |   |__temperature conditional amorphic allele - genetic evidence(+) 6 rec.
           |   |__temperature conditional amorphic allele - molecular evidence(+) 2 rec.
           |__temperature conditional hypomorphic allele 62 rec.
               |__cold sensitive hypomorphic allele(+) 7 rec.
               |__heat sensitive hypomorphic allele(+) 50 rec.
               |__temperature conditional hypomorphic allele - genetic evidence(+) 56 rec.
               |__temperature conditional hypomorphic allele - molecular evidence(+) 2 rec.
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