FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term neuroblast NB1-2 ID (Ontology) FBbt:00001384 (Fly Anatomy)
Definition Neuroblast that delaminates in the S2 wave and generates 4-6 intersegmental interneurons. It also produces approximately 20 local interneurons and, in thoracic segments, the semaphorin II (FBgn0011260) positive DC motorneuron. In the embryo, one of these cells can be found in each hemisegment from S2-A9 (Birkholz et al., 2013; Urbach et al., 2016). In the larva, it resumes proliferation in all thoracic segments and the first abdominal segment, generating secondary lineage 1 (Lacin and Truman, 2016).[ FlyBase:FBrf0055900 FlyBase:FBrf0084809 FlyBase:FBrf0112030 FlyBase:FBrf0180161 FlyBase:FBrf0221210 FlyBase:FBrf0228122 FlyBase:FBrf0231327 FlyBase:FBrf0232096 ]
Also Known As "lineage 1 neuroblast" ; "lineage NB1-2 neuroblast" ; "NB 1" (for all, see Synonyms field below)
Comment Originally referred to as NB1-1 by Doe (1992), this was renamed to NB1-2 by Broadus et al. (1995) to reflect the fact that it is the only engrailed-expressing anterior row neuroblast in both Drosophila and Schistocerca.
Links to External Ontologies
VFB:FBbt_00001384
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       1
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 Alleles Genes Insertions
 neuroblast NB1-2 (all annotations which use CV term, excluding "NOT" statements)       1     12      1
Spanning Tree (Parents/Children)
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neuroblast
 |__stage 2 neuroblast_______________
 |__segmentally-repeated neuroblast__|
ectodermal derivative                |
 |__segmentally-repeated neuroblast__|
                                     neuroblast NB1-2  14 rec.
                                      |__abdominal neuroblast NB1-2
                                      |   |__abdominal 1 neuroblast NB1-2
                                      |__labial neuroblast NB1-2
                                      |__maxillary neuroblast NB1-2
                                      |__thoracic neuroblast NB1-2
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Is a stage 2 neuroblast
segmentally-repeated neuroblast
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VFB:FBbt_00001384