Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Term | lobula columnar neuron LC4 | ID (Ontology) | FBbt:00003874 (Fly Anatomy) |
| Definition | Lobula columnar neuron whose cell body is in an extended region of the lateral cell body rind (Wu et al., 2016). It has its main dendritic arbors in lobula layers 2 and 4 (Wu et al., 2016; Tanaka and Clark, 2022). Its arbors span approximately 40 optic columns, overlapping with other LC4 cells (Wu et al., 2016). It projects to an optic glomerulus in the PVLP that is medial to the one from LC12 and ventral to LPLC2 and LPLC1 (Wu et al., 2016). There are an estimated 66 neurons of this type (Wu et al., 2016). It has been reported as being both glutamatergic (Raghu and Borst, 2011) and cholinergic (Davis et al., 2020).[ FlyBase:FBrf0049410 FlyBase:FBrf0193607 FlyBase:FBrf0213690 FlyBase:FBrf0234700 FlyBase:FBrf0244935 FlyBase:FBrf0253297 ] | ||
| Also Known As | "ColA" ; "LC04" ; "LC4" (for all, see Synonyms field below) | ||
| Comment | The glutamate neurotransmitter was assessed by labelling cells with a vGlut[CNSIII]-GAL4 driver (FBti0129148) (Raghu and Borst, 2011). The acetylcholine neurotransmitter was assessed by scRNAseq detection of choline acetyltransferase (FBgn0000303) and vesicular acetylcholine transporter (FBgn0270928) expression (Davis et al., 2020). Otsuna states that lcn4 innervates an optic glomerulus in the vlpr and vlpr maps to the VLP in Ito et al. (2014). Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB and with a presynaptic marker (synaptotagmin-HA driver) (Wu et al., 2016). | ||
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| VFB:FBbt_00003874 | |||
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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adult optic lobe columnar neuron |__lobula columnar neuron_________________ |__optic lobe wide-field columnar neuron__| cholinergic neuron | |__adult cholinergic neuron_______________| adult neuron | |__adult cholinergic neuron_______________| |__adult glutamatergic neuron_____________| adult visual projection neuron | |__lobula columnar neuron_________________| glutamatergic neuron | |__adult glutamatergic neuron_____________| lobula columnar neuron LC4 22 rec. |
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lobula columnar neuron adult cholinergic neuron adult glutamatergic neuron optic lobe wide-field columnar neuron |
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FlyBrain_NDB:10001 VFB:FBbt_00003874 |
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