FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term LNv neuron ID (Ontology) FBbt:00004046 (Fly Anatomy)
Definition Lateral period-expressing neuron (LN) of the adult brain whose cell body is located in the ventral cluster of LNs, at the level of the esophageal foramen (Helfrich-Forster, 1998). It has neurites associated with the accessory medulla (aMe) (Helfrich-Forster et al., 2007). The LN neuronal group are necessary and sufficient for generation of robust adult locomotor rhythms in the absence of environmental cues (Helfrich-Forster et al., 2007). There are approximately nine of these cells per hemisphere (Ma et al., 2021). They are peptidergic, with eight per hemisphere expressing Pdf and the other expressing ion transport peptide (Johard et al., 2009; Ma et al., 2021).[ FlyBase:FBrf0056576 FlyBase:FBrf0101921 FlyBase:FBrf0123172 FlyBase:FBrf0193849 FlyBase:FBrf0208477 FlyBase:FBrf0247880 ]
Also Known As "LNv"
Comment Assertion that LNvs are necessary and sufficient for locomotor rhythms based on mosaic analysis (Ewer et al., 1992), and by similarity of period-mutant flies to those with ablation of Pdf-expressing neurons (i.e. all LNvs except one cell), (Renn et al., 1999).
Links to External Ontologies
VFB:FBbt_00004046
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN      50
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       6
Insertions (FBti)  PHENOTYPE_MANIFEST_IN       2
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN      29
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 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes  Insertions Constructs
 LNv neuron (all annotations which use CV term, excluding "NOT" statements)      51     11      1      8     45
     LNv neuron | adult stage       2       --       --       --       2
     LNv neuron | larval stage      13       --       --       1     10
     LNv neuron | larval stage | somatic clone       2       --       --       --       2
     LNv neuron | third instar larval stage       8       --       --       --       8
Spanning Tree (Parents/Children)
Only view relationship:
peptidergic neuron
 |__adult peptidergic neuron____________
adult neuron                            |
 |__accessory medulla neuron____________|
 |__adult peptidergic neuron____________|
adult neurosecretory neuron             |
 |__neurosecretory cell of adult brain__|
neurosecretory cell of brain            |
 |__neurosecretory cell of adult brain__|
adult CNS neuron                        |
 |__LN period neuron____________________|
 |__neurosecretory cell of adult brain__|
adult pacemaker neuron                  |
 |__LN period neuron____________________|
                                        LNv neuron  454 rec.
                                         |__adult s-LNv neuron 284 rec.
                                         |   |__adult Pdf negative s-LNv neuron 40 rec.
                                         |   |__s-LNv Pdf neuron 85 rec.
                                         |__l-LNv neuron 176 rec.
                                             |__extra l-LNv neuron
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Is a LN period neuron
neurosecretory cell of adult brain
accessory medulla neuron
adult peptidergic neuron
Part of
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Synonyms
  • "lateral neuron ventral" RELATED
    "LNv" EXACT VFB_SYMBOL
    "ventral adult lateral neuron" RELATED
    "ventral lateral neurons" RELATED
Secondary IDs
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VFB:FBbt_00004046