FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term perineurial glial sheath ID (Ontology) FBbt:00007089 (Fly Anatomy)
Definition The outermost cellular layer of the nervous system, probably of mesodermal origin (Hartenstein and Jan, 1992). This layer consists of glial cells, which participate in nutrient uptake and establish a first diffusion barrier (Limmer et al., 2014).[ FlyBase:FBrf0057603 FlyBase:FBrf0058936 FlyBase:FBrf0226917 ]
Also Known As "apical glial cell" ; "perineural sheath" ; "perineurial sheath"
Comment Evidence of mesodermal origin comes from the observation that embryos lacking mesoderm lack this cell layer and the overlying neural lamella (Edwards et al., 1993).
Links to External Ontologies
VFB:FBbt_00007089
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 perineurial glial sheath (all annotations which use CV term, excluding "NOT" statements)       1
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  multicellular structure
   |__portion of tissue
       |__perineurial glial sheath  143 rec.
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Is a portion of tissue
Part of perineurium
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VFB:FBbt_00007089