FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term adult Dh44 neuron of pars intercerebralis ID (Ontology) FBbt:00047127 (Fly Anatomy)
Definition Diuretic hormone 44 (DH44)-expressing neuron of the adult having a cell body in the pars intercerebralis. There are three of these cells per hemisphere and they all coexpress leucokinin receptor (Cannell et al., 2016). These DH44 neurons synapse with Hugin neurons in the pars intercerebralis, the subesophageal zone and along the midline of the brain between these regions (King et al., 2017). Their subesophageal arborization is predominantly in the prow (Lee et al., 2015). It exits the brain via the nervus corporis cardiaci (McKim et al., 2024) and axons project to the foregut, anterior midgut and crop (Dus et al., 2015). It can be directly activated by the presence of nutritive sugars (Dus et al., 2015) or a small subset of amino acids (Yang et al., 2018) in the hemolymph.[ FlyBase:FBrf0152168 FlyBase:FBrf0227862 FlyBase:FBrf0228903 FlyBase:FBrf0232426 FlyBase:FBrf0236052 FlyBase:FBrf0240373 ]
Also Known As "adult DH44 PI neuron" ; "adult DH44+ PI neuron" ; "adult m-NSC DH44"
Comment Synapsing data shown by GRASP (King et al., 2017).
Links to External Ontologies
VFB:FBbt_00047127
Annotations
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Data Class Field Records
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       5
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Relevant FlyBase reports
 Genes Insertions Constructs
 adult Dh44 neuron of pars intercerebralis (all annotations which use CV term, excluding "NOT" statements)       3      5      6
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supraesophageal ganglion neuron
 |__adult neurosecretory cell of pars intercerebralis__
adult neuron                                           |
 |__adult gut-innervating neuron_______________________|
Dh44 neuron                                            |
 |__Dh44 neuron of pars intercerebralis________________|
 |__adult Dh44 neuron of brain_________________________|
neurosecretory cell of pars intercerebralis            |
 |__Dh44 neuron of pars intercerebralis________________|
 |__adult neurosecretory cell of pars intercerebralis__|
efferent neuron                                        |
 |__Dh44 neuron of pars intercerebralis________________|
adult efferent neuron                                  |
 |__adult ring gland projection neuron_________________|
gut-innervating neuron                                 |
 |__adult gut-innervating neuron_______________________|
neurosecretory cell of adult brain                     |
 |__adult neurosecretory cell of pars intercerebralis__|
 |__adult Dh44 neuron of brain_________________________|
adult peptidergic neuron                               |
 |__adult Dh44 neuron of brain_________________________|
                                                       adult Dh44 neuron of pars intercerebralis  14 rec.
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Is a Dh44 neuron of pars intercerebralis
adult neurosecretory cell of pars intercerebralis
adult Dh44 neuron of brain
adult gut-innervating neuron
adult ring gland projection neuron
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Synonyms
  • "adult DH44 PI neuron" EXACT
    "adult DH44+ PI neuron" EXACT[ FlyBase:FBrf0236052 ]
    "adult m-NSC DH44" EXACT
Secondary IDs
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VFB:FBbt_00047127