FB2025_05 , released December 11, 2025

General Information
Term	dorsal anterior lateral neuron of the protocerebrum	ID (Ontology)	FBbt:00059205 (Fly Anatomy)
Definition	One of the neurons of the dorsal anterior lateral group of the protocerebrum (Xia et al., 2005). It projects its axons in three different regions: the superior dorsofrontal, the dorsolateral, and the inferior dorsofrontal protocerebrum domains. It establishes synaptic contacts with the pioneer mushroom body alpha/beta neurons in a small dorsal frontal domain of the mushroom body calyx (Chen et al., 2012). These neurons are involved in the retrieval of long-term memories (Chen et al., 2012) and are synapsed to mushroom body medial lobe arborizing neuron 4 and mushroom body vertical lobe arborizing neuron 3, which are also involved in long-term memory processing (Wu et al., 2017).[ FlyBase:FBrf0187341 FlyBase:FBrf0217453 FlyBase:FBrf0236302 ]
Also Known As	"DAL neuron"
Comment	Pre-and postsynaptic sites were assessed by synaptotagmin or Dscam-GFP stainings, respectively. Synaptic input to the pioneer mushroom body alpha/beta neurons was visualized using GFP reconstitution across synaptic partners (GRASP). Function in the retrieval of long-term memory was assessed using an olfactory associative learning assay. Memory retrieval was impaired when neurotransmission was blocked using UAS-Ricin in the DAL neurons labelled with E0946-GAL4, G0338-GAL4 or G0431-GAL4. Note that DAL neurons are a subset of the neurons labeled by these GAL4 line lines, and so their identity was confirmed by immunostaining for DDC (FBgn0000422) (Chen et al., 2012). GRASP also used to show connectivity with MBON-alpha3 and MBON-beta'2mp (Wu et al., 2017).
Links to External Ontologies
	VFB:FBbt_00059205
Annotations
Records annotated with this term OR any of its CHILD TERMS
No relevant records available
Records annotated with this exact term (annotations to child terms are NOT included)
No relevant records available
Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available

General Information

Term

dorsal anterior lateral neuron of the protocerebrum

ID (Ontology)

FBbt:00059205 (Fly Anatomy)

Definition

One of the neurons of the dorsal anterior lateral group of the protocerebrum (Xia et al., 2005). It projects its axons in three different regions: the superior dorsofrontal, the dorsolateral, and the inferior dorsofrontal protocerebrum domains. It establishes synaptic contacts with the pioneer mushroom body alpha/beta neurons in a small dorsal frontal domain of the mushroom body calyx (Chen et al., 2012). These neurons are involved in the retrieval of long-term memories (Chen et al., 2012) and are synapsed to mushroom body medial lobe arborizing neuron 4 and mushroom body vertical lobe arborizing neuron 3, which are also involved in long-term memory processing (Wu et al., 2017).[ FlyBase:FBrf0187341 FlyBase:FBrf0217453 FlyBase:FBrf0236302 ]

Also Known As

"DAL neuron"

Comment

Pre-and postsynaptic sites were assessed by synaptotagmin or Dscam-GFP stainings, respectively. Synaptic input to the pioneer mushroom body alpha/beta neurons was visualized using GFP reconstitution across synaptic partners (GRASP). Function in the retrieval of long-term memory was assessed using an olfactory associative learning assay. Memory retrieval was impaired when neurotransmission was blocked using UAS-Ricin in the DAL neurons labelled with E0946-GAL4, G0338-GAL4 or G0431-GAL4. Note that DAL neurons are a subset of the neurons labeled by these GAL4 line lines, and so their identity was confirmed by immunostaining for DDC (FBgn0000422) (Chen et al., 2012). GRASP also used to show connectivity with MBON-alpha3 and MBON-beta'2mp (Wu et al., 2017).

Links to External Ontologies

VFB:FBbt_00059205

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

supraesophageal ganglion neuron__ adult CNS neuron_________________| neuron of the dorsal anterior lateral group of the protocerebrum |__dorsal anterior lateral neuron of the protocerebrum

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Is a	neuron of the dorsal anterior lateral group of the protocerebrum
Part of
Synonyms & Secondary IDs
Synonyms
	"DAL neuron" EXACT[ FlyBase:FBrf0187341 ]
Secondary IDs

External Crossreferences & Linkouts
	VFB:FBbt_00059205

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Parents/Children
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Relationships

Is a

neuron of the dorsal anterior lateral group of the protocerebrum

Part of

Synonyms & Secondary IDs

Synonyms

"DAL neuron" EXACT[ FlyBase:FBrf0187341 ]

Secondary IDs

External Crossreferences & Linkouts

VFB:FBbt_00059205