FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term adult dopaminergic PAM neuron ID (Ontology) FBbt:00100214 (Fly Anatomy)
Definition A dopaminergic neuron whose cell body is located in a cluster of approximately 100 cell bodies in the cortex of the anterior inferior medial protocerebrum of the adult brain (Mao and Davis, 2009). There are multiple subtypes, of which most (but not all) target the medial lobe (Li et al., 2020). They all follow a mushroom body commissure to the contralateral mushroom body (Li et al., 2020). They are secondary neurons, with some belonging to the CREa1A (BAMd1A) hemilineage and some belonging to the CREa2A (DALcm1A) hemilineage (Lee et al., 2020; Truman et al., 2023).[ FlyBase:FBrf0208427 FlyBase:FBrf0227179 FlyBase:FBrf0248215 FlyBase:FBrf0255928 ]
Also Known As "adult dopaminergic PAM1 neuron" ; "AM cell cluster neuron" ; "PAM" (for all, see Synonyms field below)
Comment The cluster of PAM neurons was judged by a curator to correspond to the AM cell cluster in Budnik and White (1988).
Links to External Ontologies
VFB:FBbt_00100214
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN      31
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION      22
Insertions (FBti)  PHENOTYPE_MANIFEST_IN       6
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN      24
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles  Genes  Insertions Constructs
 adult dopaminergic PAM neuron (all annotations which use CV term, excluding "NOT" statements)      31      7      2     17     28     51
     adult dopaminergic PAM neuron | adult stage       8       --       --       --       1      7
     adult dopaminergic PAM neuron | adult stage | decreased number      16       --       --       --       5     13
     adult dopaminergic PAM neuron | adult stage | progressive       2       --       --       --       1       --
     adult dopaminergic PAM neuron | decreased number       5       --       --       --       --       4
     adult dopaminergic PAM neuron | decreased number | larval stage       1       --       --       --       1       --
     adult dopaminergic PAM neuron | progressive       2       --       --       --       --       1
Spanning Tree (Parents/Children)
Only view relationship: 
secondary neuron
 |__Notch ON hemilineage secondary neuron__________
adult mushroom body modulatory input neuron        |
 |__adult dopaminergic mushroom body input neuron__|
mushroom body dopaminergic neuron                  |
 |__adult dopaminergic mushroom body input neuron__|
Notch ON hemilineage neuron                        |
 |__Notch ON hemilineage secondary neuron__________|
adult dopaminergic neuron                          |
 |__adult dopaminergic mushroom body input neuron__|
CNS neuron                                         |
 |__supraesophageal ganglion neuron________________|
                                                   adult dopaminergic PAM neuron  244 rec.
                                                    |__dopaminergic PAM neuron 1 45 rec.
                                                    |   |__PAM01 neuron of upper MB commissure 1 rec.
                                                    |   |__PAM01 neuron of ventral MB commissure(+) 4 rec.
                                                    |__dopaminergic PAM neuron 2 29 rec.
                                                    |__dopaminergic PAM neuron 3 22 rec.
                                                    |__dopaminergic PAM neuron 5 31 rec.
                                                    |__dopaminergic PAM neuron 6 36 rec.
                                                    |__dopaminergic PAM neuron 7 18 rec.
                                                    |__dopaminergic PAM neuron 8 22 rec.
                                                    |__dopaminergic PAM neuron 9 4 rec.
                                                    |__dopaminergic PAM neuron 11 29 rec.
                                                    |__dopaminergic PAM neuron 12 31 rec.
                                                    |__dopaminergic PAM neuron 13 36 rec.
                                                    |__dopaminergic PAM neuron 14 37 rec.
                                                    |__dopaminergic PAM neuron 15
                                                    |__mushroom body medial lobe arborizing neuron 8 40 rec.
                                                        |__dopaminergic PAM neuron 4 21 rec.
                                                        |__dopaminergic PAM neuron 10 33 rec.
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Is a supraesophageal ganglion neuron
Notch ON hemilineage secondary neuron
adult dopaminergic mushroom body input neuron
Part of adult brain
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Synonyms
  • "adult dopaminergic PAM1 neuron" EXACT[ FlyBase:FBrf0234128 ]
    "AM cell cluster neuron" EXACT[ FlyBase:FBrf0048550 ]
    "PAM" EXACT VFB_SYMBOL[ FlyBase:FBrf0208427 ]
    "PAM cluster neuron" EXACT
    "protocerebral anteriomedial dopaminergic cluster neuron" EXACT
    "protocerebral anterior medial dopaminergic cluster neuron" RELATED
    "TH-positive anteriomedial cluster neuron" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
FlyBrain_NDB:10447
VFB:FBbt_00100214