FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term dopaminergic PPM1 neuron ID (Ontology) FBbt:00100216 (Fly Anatomy)
Definition Dopaminergic neuron whose cell body is located in a small cluster along the dorsoventral midline of the posterior superior medial protocerebrum of the adult brain.[ FlyBase:FBrf0208427 ]
Also Known As "PPM1" ; "PPM1 cluster neuron" ; "protocerebral posteriomedial dopaminergic neuron 1" (for all, see Synonyms field below)
Comment Mao and Davis (2009) identify 8 protocerebral clusters coincidentally positive for TH-GAL4 activity and tyrosine hydroxylase immunoreactivity, implying these cells are dopaminergic. They refer to the protocerebral posteriomedial dopaminergic neuron 1 as a cluster. Hartenstein et al. (2017) - FBrf0234128 show that the larval DM1 cluster (primary DPMm1/l1 lineages) becomes the adult PPM1 cluster, but unclear whether any adult cells do not derive from functional larval primary neurons.
Links to External Ontologies
VFB:FBbt_00100216
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN      46
Insertions (FBti)  PHENOTYPE_MANIFEST_IN       3
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN      39
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 Full annotation statements 
Relevant FlyBase reports
 Alleles  Genes Insertions Constructs
 dopaminergic PPM1 neuron (all annotations which use CV term, excluding "NOT" statements)      46     15      2      3     62
     dopaminergic PPM1 neuron | adult stage      19       --       --       2     17
     dopaminergic PPM1 neuron | adult stage | decreased number       4       --       --       --       3
     dopaminergic PPM1 neuron | adult stage | increased number       2       --       --       --       2
     dopaminergic PPM1 neuron | adult stage | progressive      10       --       --       --      10
     dopaminergic PPM1 neuron | decreased number       6       --       --       1      4
     dopaminergic PPM1 neuron | progressive       4       --       --       --       3
Spanning Tree (Parents/Children)
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dopaminergic neuron
 |__adult dopaminergic neuron________
adult neuron                         |
 |__adult CNS neuron_________________|
adult aminergic neuron               |
 |__adult dopaminergic neuron________|
CNS neuron                           |
 |__supraesophageal ganglion neuron__|
 |__adult CNS neuron_________________|
                                     dopaminergic PPM1 neuron  128 rec.
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Is a supraesophageal ganglion neuron
adult dopaminergic neuron
adult CNS neuron
Part of adult brain
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Synonyms
  • "PPM1" EXACT VFB_SYMBOL[ FlyBase:FBrf0208427 ]
    "PPM1 cluster neuron" EXACT
    "protocerebral posteriomedial dopaminergic neuron 1" EXACT
    "protocerebral posterior medial dopaminergic neuron 1" EXACT
    "TH-positive posterior medial cluster 1 neuron" EXACT
Secondary IDs
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VFB:FBbt_00100216