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| Term | dopaminergic PPM3 neuron | ID (Ontology) | FBbt:00100218 (Fly Anatomy) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Definition | A dopaminergic neuron whose cell body is located in a cluster in the cortex of the superior posterior slope of the adult brain (Mao and Davis, 2009). There are approximately 8-9 of these cells and their axons project along the medial equatorial fascicle to the central complex and adjacent neuropil regions (Omoto et al., 2018). It belongs to the DM6 (CM3) primary lineage (Ren et al., 2016; Hartenstein et al., 2017; Schlegel et al., 2024), but does not mature until metamorphosis (Hartenstein et al., 2017).[ FlyBase:FBrf0048550 FlyBase:FBrf0208427 FlyBase:FBrf0233706 FlyBase:FBrf0234128 FlyBase:FBrf0240929 FlyBase:FBrf0260535 ] | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Also Known As | "PM cell cluster neuron" ; "PPM3" ; "PPM3 cluster neuron" (for all, see Synonyms field below) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Comment | Mao and Davis (2009) identify 8 protocerebral clusters coincidentally positive for TH-GAL4 activity and tyrosine hydroxylase immunoreactivity, implying these cells are dopaminergic. The cluster of PPM3 neurons was judged by a curator to correspond to the PM cell cluster in Budnik and White (1988). Hartenstein et al. (2017) map PPM3 to CM4 (DM4) primary lineage based on morphology and HU application, Ren et al. (2016) - map to CM3 (DM6) secondary lineage based on markers and heat shock induction, Schlegel et al. (2024) assign all subtypes as DM6 primary neurons based on EM. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Links to External Ontologies | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| VFB:FBbt_00100218 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Annotations | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Records annotated with this term OR any of its CHILD TERMS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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neuron |__primary neuron___________________ dopaminergic neuron | |__adult dopaminergic neuron________| adult neuron | |__adult central complex neuron_____| CM3 lineage neuron | |__adult DM6 lineage neuron_________| adult aminergic neuron | |__adult dopaminergic neuron________| CNS neuron | |__supraesophageal ganglion neuron__| adult CNS neuron | |__adult DM6 lineage neuron_________| dopaminergic PPM3 neuron 162 rec. |__EB neuron of the dopaminergic PPM3 cluster 28 rec. |__mFB neuron of the dopaminergic PPM3 cluster 33 rec. | |__dopaminergic PPM3 fan-shaped body layer 4 neuron | |__dopaminergic PPM3 fan-shaped body layer 4-nodulus neuron |__vFB neuron of the dopaminergic PPM3 cluster 39 rec. |
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Relationships
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| Is a |
supraesophageal ganglion neuron primary neuron adult central complex neuron adult DM6 lineage neuron adult dopaminergic neuron |
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| Develops from | immature dopaminergic PPM3 neuron | ||
| Part of | adult brain | ||
Synonyms & Secondary IDs
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External Crossreferences & Linkouts
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| VFB:FBbt_00100218 | |||