FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term larval VUM motor neuron ID (Ontology) FBbt:00110181 (Fly Anatomy)
Definition Motor neuron that develops from a VUM precursor (midline precursors 4-6) (Crews, 2019). There are three of these cells per segment (Schmid et al., 1999). They are modulatory motor neurons; in A1-7, one VUM motor neuron innervates the dorsal muscles, one innervates the ventral muscles, and one innervates the lateral muscles. These neurons are all octopaminergic and tyraminergic (Stocker et al., 2018).[ FlyBase:FBrf0072659 FlyBase:FBrf0112030 FlyBase:FBrf0180108 FlyBase:FBrf0238580 FlyBase:FBrf0244240 ]
Also Known As "larval vumTDC2 neuron" ; "mVUM" ; "ventral unpaired motorneuron" (for all, see Synonyms field below)
Comment Wheeler et al. (2006) - FBrf0195284 showed expression of the vesicular glutamate transporter (vGlut), tyramine beta-hydroxylase (Tbh) and the vesicular monoamine transporter (Vmat). Vomel and Wegener (2008) used Tdc2-GAL4 and anti-Tbh. Selcho et al. (2012) used Tdc2-GAL4, validated with anti-Tbh, anti-p-tyramine and anti-conjugated octopamine. Stocker et al. (2018) used octopamine and tyramine antibodies. VUM neurons are found in thoracic and abdominal segments (Schmid et al., 1999). Seem to be the only type II MN to innervate body wall (hypodermal) muscles.
Links to External Ontologies
VFB:FBbt_00110181
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN       3
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       4
Insertions (FBti)  PHENOTYPE_MANIFEST_IN       1
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN       1
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Insertions Constructs
 larval VUM motor neuron (all annotations which use CV term, excluding "NOT" statements)       3     19      5      2
     larval VUM motor neuron | embryonic stage 16 | increased number       2       --       --       --
Spanning Tree (Parents/Children)
Only view relationship: 
larval neuron
 |__larval glutamatergic neuron____
motor neuron                       |
 |__type II motor neuron___________|
octopaminergic neuron              |
 |__type II motor neuron___________|
 |__larval octopaminergic neuron___|
larval efferent neuron             |
 |__embryonic/larval motor neuron__|
primary motor neuron               |
 |__embryonic/larval motor neuron__|
larval aminergic neuron            |
 |__larval octopaminergic neuron___|
 |__larval tyraminergic neuron_____|
glutamatergic neuron               |
 |__larval glutamatergic neuron____|
tyraminergic neuron                |
 |__larval tyraminergic neuron_____|
larval ventral midline neuron      |
 |__larval VUM neuron______________|
                                   larval VUM motor neuron  33 rec.
                                    |__larval dorsal VUM motor neuron 4 rec.
                                    |   |__larval A1-7-innervating dorsal VUM motor neuron(+) 3 rec.
                                    |__larval lateral VUM motor neuron 3 rec.
                                    |   |__larval A1-7-innervating lateral VUM motor neuron(+) 3 rec.
                                    |__larval mesothoracic VUM motor neuron
                                    |__larval metathoracic VUM motor neuron
                                    |__larval prothoracic VUM motor neuron
                                    |__larval ventral VUM motor neuron 4 rec.
                                        |__larval A1-7-innervating ventral VUM motor neuron(+) 3 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a larval VUM neuron
embryonic/larval motor neuron
type II motor neuron
larval octopaminergic neuron
larval tyraminergic neuron
larval glutamatergic neuron
Part of
hide Synonyms & Secondary IDs
Synonyms
Secondary IDs
hide External Crossreferences & Linkouts
VFB:FBbt_00110181