FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term MB-alpha neuron of the dopaminergic PPL1 cluster ID (Ontology) FBbt:00110320 (Fly Anatomy)
Definition PPL1 cluster dopaminergic neuron with axonal projections to the tip of the mushroom body alpha lobe (segment 3) (Mao and Davis, 2009; Aso et al., 2014) in both hemispheres (Li et al., 2020). Most of its dendritic arborizations are found in the superior medial and lateral protocerebrum, with a smaller amount in the superior intermediate protocerebrum and lateral horn (Aso et al., 2014). There is one neuron of this type in each hemisphere (Aso et al., 2014; Li et al., 2020) and it develops from the first intermediate neuronal progenitor the CP3 (DL2) neuroblast to be born during larval development (Wang et al., 2014; Ren et al., 2016).[ FlyBase:FBrf0208427 FlyBase:FBrf0223600 FlyBase:FBrf0227179 FlyBase:FBrf0233706 FlyBase:FBrf0248215 ]
Also Known As "PPL1-06" ; "PPL1-alpha3" ; "PPL106"
Comment The PPL1 cluster was identified by TH immunostaining and using a TH-GAL4 driver (FBtp0020119).
Links to External Ontologies
VFB:FBbt_00110320
Annotations
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Data Class Field Records
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       4
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  Insertions Constructs
 MB-alpha neuron of the dopaminergic PPL1 cluster (all annotations which use CV term, excluding "NOT" statements)      35      4     29
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neuron
 |__secondary neuron_______________
mushroom body dopaminergic neuron  |
 |__mushroom body PPL1 neuron______|
adult CNS neuron                   |
 |__adult DL2 lineage neuron_______|
dopaminergic PPL1 neuron           |
 |__mushroom body PPL1 neuron______|
CP3 lineage neuron                 |
 |__adult DL2 lineage neuron_______|
                                   MB-alpha neuron of the dopaminergic PPL1 cluster  68 rec.
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Is a secondary neuron
mushroom body PPL1 neuron
adult DL2 lineage neuron
Develops from DL2 secondary intermediate neural progenitor 1
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VFB:FBbt_00110320