FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term larval pharynx-innervating Hugin neuron ID (Ontology) FBbt:00110350 (Fly Anatomy)
Definition Larval Hugin neuron that projects to the anterior pharynx. The neurites leave the subesophageal ganglion, make a U-turn and terminate at the anterior region of the dorsal pharyngeal muscles. This neuron is part of the dopaminergic SM1 cluster of the larval brain. There are two of these cells per hemisphere, the vast majority of their synaptic inputs are from interneurons, and they do not have synaptic outputs within the central nervous system (Schlegel et al., 2016).[ FlyBase:FBrf0188215 FlyBase:FBrf0200884 FlyBase:FBrf0208252 FlyBase:FBrf0234450 ]
Also Known As "hugin-PH" ; "larval dopaminergic SM1-2 neuron" ; "larval Hugin neuron of the pharynx" (for all, see Synonyms field below)
Comment This neuron was described as dopaminergic because it is labelled by the driver TH-GAL4 (FBtp0020119) although it is not positive for the anti-TH antibody (Selcho et al., 2009). A subset of the pharynx and the VNC hugin neurons expresses ChAT and this expression is required for full Hugin neuron function - i.e. some neurons of this class may be cholinergic (Schlegel et al., 2016). Synapsing identified in full L1 VNC EM volume - approximately 97 percent of synapses are with interneurons (Schlegel et al., 2016).
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VFB:FBbt_00110350
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 larval pharynx-innervating Hugin neuron (all annotations which use CV term, excluding "NOT" statements)       2      3
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larval neuron
 |__larval gut-innervating neuron___
gnathal ganglion neuron             |
 |__larval dopaminergic SM1 neuron__|
 |__larval Hugin neuron_____________|
gut-innervating neuron              |
 |__larval gut-innervating neuron___|
larval peptidergic neuron           |
 |__larval Hugin neuron_____________|
larval dopaminergic neuron          |
 |__larval dopaminergic SM1 neuron__|
larval CNS neuron                   |
 |__larval dopaminergic SM1 neuron__|
 |__larval Hugin neuron_____________|
Hugin neuron                        |
 |__larval Hugin neuron_____________|
                                    larval pharynx-innervating Hugin neuron  5 rec.
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Is a larval gut-innervating neuron
larval dopaminergic SM1 neuron
larval Hugin neuron
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VFB:FBbt_00110350