FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term apterous-expressing neuron of the lateral cluster of the thorax ID (Ontology) FBbt:00110868 (Fly Anatomy)
Definition Primary interneuron that expresses apterous and is found in a relatively lateral position within an embryonic or larval thoracic neuromere (Lundgren et al., 1995). There are four of these neurons per thoracic hemisegment and they are born at the end of the primary lineage of NB5-6T, with Ap1 generated at stage 13, followed by Ap2, Ap3 and Ap4 (Baumgardt et al., 2007; Baumgardt et al., 2009). They are generated directly from the neuroblast, without a ganglion mother cell intermediate (Baumgardt et al., 2009).[ FlyBase:FBrf0078940 FlyBase:FBrf0184217 FlyBase:FBrf0195184 FlyBase:FBrf0209429 ]
Also Known As "Ap cluster" ; "ap cluster" ; "Ap cluster neuron"
Comment Non-thoracic segments may have dorsal and ventral Ap neurons, but no lateral clusters.
Links to External Ontologies
VFB:FBbt_00110868
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN     101
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       1
Insertions (FBti)  PHENOTYPE_MANIFEST_IN       3
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN      10
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 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Insertions Constructs
 apterous-expressing neuron of the lateral cluster of the thorax (all annotations which use CV term, excluding "NOT" statements)     101      7      4     11
     apterous-expressing neuron of the lateral cluster of the thorax | ectopic      23       --       --       --
     apterous-expressing neuron of the lateral cluster of the thorax | embryonic stage       3       --       1       --
     apterous-expressing neuron of the lateral cluster of the thorax | embryonic stage | increased number       9       --       --       2
     apterous-expressing neuron of the lateral cluster of the thorax | late embryonic stage      11       --       --       2
Spanning Tree (Parents/Children)
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lineage NB5-6 primary interneuron__
thoracic neuron____________________|
ventral ectoderm derivative________|
larval interneuron_________________|
                                   larval thoracic NB5-6 primary interneuron
                                    |__apterous-expressing neuron of the lateral cluster of the thorax  171 rec.
                                        |__apterous-expressing neuron of the lateral cluster of the thorax Ap1 14 rec.
                                        |__apterous-expressing neuron of the lateral cluster of the thorax Ap2 3 rec.
                                        |__apterous-expressing neuron of the lateral cluster of the thorax Ap3 2 rec.
                                        |__apterous-expressing neuron of the lateral cluster of the thorax Ap4 121 rec.
                                            |__larval mesothoracic Ap4 neuron
                                            |__larval metathoracic Ap4 neuron
                                            |__larval prothoracic Ap4 neuron
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Is a larval thoracic NB5-6 primary interneuron
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VFB:FBbt_00110868