FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term peripheral cell ID (Ontology) FBbt:00110875 (Fly Anatomy)
Definition A cell in the larval midgut and early pupal midgut that extends its processes around the midgut imaginal islands (Mathur et al., 2010). These cells are formed at late second larval instar, usually by the first, asymmetric, division of an adult midgut progenitor cell (AMP) (Mathur et al., 2010). There is usually one peripheral cell per imaginal island (Mathur et al., 2010). These cells undergo apoptosis shortly after pupariation (0-2h APF) and do not contribute to the adult midgut (Mathur et al., 2010). Peripheral cells act as a niche for AMPs to keep them undifferentiated until metamorphosis (Mathur et al., 2010).[ FlyBase:FBrf0209706 ]
Also Known As "niche peripheral cell" ; "PC" ; "transient pupal midgut cell"
Comment These cells can be identified by their expression of a Su(H)GBE reporter, indicating active Notch signaling (Mathur et al., 2010).
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Data Class Field Records
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       1
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 peripheral cell (all annotations which use CV term, excluding "NOT" statements)       2      1      2
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  somatic cell
   |__embryonic/larval midgut cell
       |__peripheral cell  5 rec.
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Is a embryonic/larval midgut cell
Develops from adult midgut progenitor cell
Part of midgut imaginal island
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