FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term larval protocerebrum-innervating Hugin neuron ID (Ontology) FBbt:00110922 (Fly Anatomy)
Definition Cholinergic larval neuron that expresses Hugin (FBgn0028374) and that arborizes in the protocerebrum (Bader et al., 2007; Schlegel et al., 2016). This neuron arborizes in the ipsilateral or both hemispheres of the protocerebrum and the ventrolateral region of the esophagus foramen. As well as receiving inputs in the subesophageal ganglion, they also have outputs in the subesophageal ganglion. There are four of these neurons per hemisphere and they form reciprocal ipsilateral connections amongst themselves and also have outputs to insulin secreting cells of the pars intercerebralis (Schlegel et al., 2016). Much of their synaptic input is from sensory neurons (Schlegel et al., 2016).[ FlyBase:FBrf0188215 FlyBase:FBrf0200884 FlyBase:FBrf0234450 ]
Also Known As "hugin-PC" ; "larval hugin cell of the protocerebrum" ; "larval Hugin neuron of the protocerebrum"
Comment Synapsing identified in full L1 VNC EM volume - all hugin-PC cells have presynaptic connections to multiple insulin cells and up to 39 percent of synaptic input is from sensory neurons (Schlegel et al., 2016).
Links to External Ontologies
VFB:FBbt_00110922
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 larval protocerebrum-innervating Hugin neuron (all annotations which use CV term, excluding "NOT" statements)       2      3
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larval neuron
 |__larval cholinergic neuron__
cholinergic neuron             |
 |__larval cholinergic neuron__|
gnathal ganglion neuron        |
 |__larval Hugin neuron________|
larval peptidergic neuron      |
 |__larval Hugin neuron________|
larval CNS neuron              |
 |__larval Hugin neuron________|
Hugin neuron                   |
 |__larval Hugin neuron________|
                               larval protocerebrum-innervating Hugin neuron  5 rec.
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Is a larval cholinergic neuron
larval Hugin neuron
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Synonyms
  • "hugin-PC" EXACT[ FlyBase:FBrf0234450 ]
    "larval hugin cell of the protocerebrum" EXACT
    "larval Hugin neuron of the protocerebrum" EXACT
Secondary IDs
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VFB:FBbt_00110922