FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term adult thermosensory neuron Ir21a VP1l ID (Ontology) FBbt:00111336 (Fly Anatomy)
Definition Thermosensory receptor neuron that expresses the Ionotropic receptor (Ir) 21a and innervates antennal lobe glomerulus VP1l (Marin et al., 2020; Alpert et al., 2020). It has its sensory dendrite in chamber I of the sacculus and it responds to temperature drops below 25 degrees celsius (Marin et al., 2020; Alpert et al., 2020). It develops from an Naa precursor (Benton et al., 2025). There are around 6-8 of these cells per hemisphere (Marin et al., 2020) and they are unilateral (Schlegel et al., 2021).[ FlyBase:FBrf0215822 FlyBase:FBrf0246007 FlyBase:FBrf0246456 FlyBase:FBrf0249560 FlyBase:FBrf0262710 ]
Also Known As "HRN_VP1l" ; "ionotropic receptor neuron Ir21a" ; "Ir21a" (for all, see Synonyms field below)
Comment Ir21a neuron of sacculus in original reference was speculatively assigned to sacculus chamber III and VP3 (Silbering et al., 2011). Later found to be chamber I and VP1l (Marin et al., 2020 and refs therein). Assigned to 'cold glomerulus' in Alpert et al. (2020) - FBrf0246007, but projections in AL look like VP1l projections shown in Marin et al. (2020).
Links to External Ontologies
VFB:FBbt_00111336
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sensory neuron
 |__external sense organ sensory neuron_______
sensory organ cell                            |
 |__external sense organ sensory neuron_______|
thermosensory neuron                          |
 |__adult thermosensory neuron________________|
adult antennal lobe receptor neuron           |
 |__unilateral antennal lobe receptor neuron__|
adult sensory neuron                          |
 |__adult thermosensory neuron________________|
PNS neuron                                    |
 |__external sense organ sensory neuron_______|
                                              adult thermosensory neuron Ir21a VP1l
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Is a adult thermosensory neuron
unilateral antennal lobe receptor neuron
external sense organ sensory neuron
Develops from antennal olfactory receptor neuron precursor Naa
Part of adult peripheral nervous system
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VFB:FBbt_00111336