FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term larval excitatory interneuron eIN-3 ID (Ontology) FBbt:00111732 (Fly Anatomy)
Definition Larval excitatory interneuron (eIN) (Zwart et al., 2016) that is early-born in the NB1-2 Notch ON primary hemilineage (Mark et al., 2021). From a ventrolateral soma, it crosses the midline and extends laterally and posteriorly, with predominantly contralateral pre- and post-synapses (Kohsaka et al., 2019; Zarin et al., 2019). Its input synapses are mainly in the same neuromere as the soma and its output synapses are mainly in the next posterior neuromere (Kohsaka et al., 2019). It outputs onto a set of contralateral transverse motor neurons, including MN-LT1-4 (Zwart et al., 2016) as well as other premotor neurons (Kohsaka et al., 2019). It is specifically involved in forwards locomotion (Kohsaka et al., 2019).[ FlyBase:FBrf0231327 FlyBase:FBrf0233076 FlyBase:FBrf0238464 FlyBase:FBrf0242656 FlyBase:FBrf0244727 FlyBase:FBrf0249021 ]
Also Known As "eIN-3" ; "Ifb-Fwd" ; "intersegmental feedback during forward propagation" (for all, see Synonyms field below)
Comment A01d3 renamed to A01d2 in Mark et al. (2021) supplement, based on catmaid skid.
Links to External Ontologies
VFB:FBbt_00111732
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 larval excitatory interneuron eIN-3 (all annotations which use CV term, excluding "NOT" statements)       1      2
Spanning Tree (Parents/Children)
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Notch ON hemilineage primary neuron
 |__NB1-2 Notch ON hemilineage primary neuron__
NB1-2 lineage primary neuron                   |
 |__lineage NB1-2 primary interneuron__________|
 |__NB1-2 Notch ON hemilineage primary neuron__|
larval premotor neuron                         |
 |__larval excitatory interneuron eIN__________|
larval interneuron                             |
 |__larval excitatory interneuron eIN__________|
primary interneuron                            |
 |__lineage NB1-2 primary interneuron__________|
 |__larval excitatory interneuron eIN__________|
larval cholinergic neuron                      |
 |__larval excitatory interneuron eIN__________|
                                               larval excitatory interneuron eIN-3  3 rec.
                                                |__larval abdominal 1 eIN-3 neuron
                                                |__larval abdominal 2 eIN-3 neuron
                                                |__larval abdominal 3 eIN-3 neuron
                                                |__larval abdominal 4 eIN-3 neuron
                                                |__larval metathoracic eIN-3 neuron
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Is a lineage NB1-2 primary interneuron
NB1-2 Notch ON hemilineage primary neuron
larval excitatory interneuron eIN
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Synonyms
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VFB:FBbt_00111732