FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term neuroblast NB3-4 ID (Ontology) FBbt:00001414 (Fly Anatomy)
Definition Neuroblast that delaminates at S5 and produces a motorneuron, located on the posterior boundary of the clone, that projects into the anterior root of the ISN, as well as several interneurons (Schmid et al., 1999). In the embryo, one of these cells can be found in each hemisegment from S1-A10 (Birkholz et al., 2013; Urbach et al., 2016). In the larva, it resumes proliferation in all thoracic segments, producing postembryonic lineage 25, which contains motor neurons and glia (Lacin and Truman, 2016).[ FlyBase:FBrf0112030 FlyBase:FBrf0221210 FlyBase:FBrf0228122 FlyBase:FBrf0231327 FlyBase:FBrf0232096 ]
Also Known As "lineage 25 neuroblast" ; "lineage NB3-4 neuroblast" ; "NB 25" (for all, see Synonyms field below)
Comment Birkholz et al. (2015) suggest that NB3-4 generates postembryonic lineage 18, but Lacin and Truman (2016) identify lineage 25 and provide lineage tracing data showing that it is generated by NB3-4. Lacin and Truman (2016) only find this cell in thoracic segments in the embryo.
Links to External Ontologies
VFB:FBbt_00001414
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       4
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Relevant FlyBase reports
 Alleles  Genes Insertions Constructs
 neuroblast NB3-4 (all annotations which use CV term, excluding "NOT" statements)       1      2      6      4      5
Spanning Tree (Parents/Children)
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neuroblast
 |__stage 5 neuroblast_______________
 |__neuroglioblast___________________|
 |__segmentally-repeated neuroblast__|
ectodermal derivative                |
 |__segmentally-repeated neuroblast__|
                                     neuroblast NB3-4  18 rec.
                                      |__abdominal neuroblast NB3-4
                                      |__labial neuroblast NB3-4
                                      |__mandibular neuroblast NB3-4
                                      |__maxillary neuroblast NB3-4
                                      |__thoracic neuroblast NB3-4
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Is a stage 5 neuroblast
neuroglioblast
segmentally-repeated neuroblast
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VFB:FBbt_00001414