FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term l-LNv neuron ID (Ontology) FBbt:00003763 (Fly Anatomy)
Definition Neuron of the period-expressing LNv cluster of the adult brain, with a large cell body and generally located more dorsally than the s-LNv neurons (Helfrich-Forster, 1998). There are four of these cells per hemisphere, all of which express Pdf (Helfrich-Forster et al., 2007). These neurons send dendrites through the posterior optic commissure to the contralateral optic lobe, where a few short fibers terminate in the accessory medulla, but most arborize extensively in the medulla itself (Helfrich-Forster, 2005; Helfrich-Forster et al., 2007). These arborizations in the medulla are associated with varicosities. These cells also project to the ipsilateral (adjacent) accessory medulla and its ventral extension, where they arborize extensively.[ FlyBase:FBrf0101921 FlyBase:FBrf0134807 FlyBase:FBrf0151380 FlyBase:FBrf0183981 FlyBase:FBrf0193849 ]
Also Known As "l-LNv" ; "l-vLN" ; "large LNv" (for all, see Synonyms field below)
Comment While l-LNv neurons fit the definition of pacemaker neurons based on molecular oscillation of Period (FBgn0003068) and Timeless (FBgn0014396) expression, they do not sustain this molecular oscillation when kept in constant darkness (Yang and Sehgal, 2001; Shafer et al., 2002). Synaptobrevin localization supports the assertion that projections through the posterior optic commissure to the contralateral optic lobe are dendritic (Helfrich-Forster et al., 2007).
Links to External Ontologies
VFB:FBbt_00003763
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN      48
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION      12
Insertions (FBti)  PHENOTYPE_MANIFEST_IN       5
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN      34
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 Full annotation statements 
Relevant FlyBase reports
 Alleles  Genes Insertions Constructs
 l-LNv neuron (all annotations which use CV term, excluding "NOT" statements)      51      5     22     17     81
     l-LNv neuron | adult stage      21       --       --       3     15
     l-LNv neuron | conditional       4       --       --       1      3
     l-LNv neuron | heat sensitive       2       --       --       --       2
     l-LNv neuron | P-stage       1       --       --       --       --
     l-LNv neuron | RU486 conditional       2       --       --       --       2
Spanning Tree (Parents/Children)
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LN period neuron
 |__LN Pdf neuron___________________
 |__LNv neuron______________________|
photoreceptor neuron                |
 |__LN Pdf neuron___________________|
neurosecretory cell of adult brain  |
 |__LN Pdf neuron___________________|
 |__LNv neuron______________________|
accessory medulla neuron            |
 |__LNv neuron______________________|
adult peptidergic neuron            |
 |__LNv neuron______________________|
adult sensory neuron                |
 |__LN Pdf neuron___________________|
adult Pdf neuron                    |
 |__LN Pdf neuron___________________|
                                    l-LNv neuron  176 rec.
                                     |__extra l-LNv neuron
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Is a LN Pdf neuron
LNv neuron
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Synonyms
  • "l-LNv" EXACT VFB_SYMBOL
    "l-vLN" EXACT[ FlyBase:FBrf0209505 ]
    "large LNv" EXACT
    "large pigment-dispersing hormone-immunoreactive neuron close to medulla" EXACT
    "lLNv" EXACT
Secondary IDs
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VFB:FBbt_00003763