FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term lineage 24 secondary neuron ID (Ontology) FBbt:00048911 (Fly Anatomy)
Definition Any neuron that develops from neuroblast NB4-4 during the postembryonic phase of neurogenesis. These are all Notch OFF hemilineage neurons, as the Notch ON hemilineage is eliminated by apoptosis (Lacin et al., 2019). In the adult, these are all glutamatergic motor neurons (Lacin et al., 2019).[ FlyBase:FBrf0231327 FlyBase:FBrf0242251 ]
Also Known As "hemilineage 24B larval-born neuron" ; "hemilineage 24B postembryonic neuron" ; "hemilineage 24B secondary neuron" (for all, see Synonyms field below)
Comment 24B sometimes referred to as 24A in Lacin et al. (2019), but lineage 24 seems to only produce 'B' neurons based on Truman et al. (2010) - FBrf0209606.
Links to External Ontologies
VFB:FBbt_00048911
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Spanning Tree (Parents/Children)
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ectodermal derivative
 |__NB4-4 lineage neuron____________________
secondary neuron                            |
 |__Notch OFF hemilineage secondary neuron__|
Notch OFF hemilineage neuron                |
 |__Notch OFF hemilineage secondary neuron__|
CNS neuron                                  |
 |__NB4-4 lineage neuron____________________|
                                            lineage 24 secondary neuron
                                             |__early-born lineage 24 intracoxal trochanter levator muscle motor neuron
                                             |__femoral depressor motor neuron Tr2
                                             |__late-born lineage 24 intracoxal trochanter levator muscle motor neuron
                                             |__lineage 24 secondary femoral reductor muscle motor neuron
                                             |__slow tibial extensor motor neuron
                                                 |__mesothoracic slow tibial extensor motor neuron
                                                 |__metathoracic slow tibial extensor motor neuron
                                                 |__prothoracic slow tibial extensor motor neuron
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Is a NB4-4 lineage neuron
Notch OFF hemilineage secondary neuron
Part of
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Synonyms
  • "hemilineage 24B larval-born neuron" EXACT
    "hemilineage 24B postembryonic neuron" EXACT
    "hemilineage 24B secondary neuron" EXACT
    "lineage 24 larval-born neuron" EXACT
    "lineage 24 postembryonic neuron" EXACT
    "lineage 24 secondary neuron" EXACT SECONDARY_VNC_LINEAGE[ FlyBase:FBrf0228122 FlyBase:FBrf0231327 ]
    "NB4-4 hemilineage B larval-born neuron" EXACT
    "NB4-4 hemilineage B postembryonic neuron" EXACT
    "NB4-4 hemilineage B secondary neuron" EXACT
    "NB4-4 lineage larval-born neuron" EXACT
    "NB4-4 lineage postembryonic neuron" EXACT
    "NB4-4 lineage secondary neuron" EXACT PRIMARY_VNC_LINEAGE[ FlyBase:FBrf0228122 FlyBase:FBrf0231327 ]
    "NB4-4 Notch OFF hemilineage larval-born neuron" EXACT
    "NB4-4 Notch OFF hemilineage postembryonic neuron" EXACT
    "NB4-4 Notch OFF hemilineage secondary neuron" EXACT
Secondary IDs
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VFB:FBbt_00048911